Interaction of chloropromazine with adrenochrome and interference of a possible endogenous psychotogenic agent with some synaptic enzyme activities
Abstract
Chloropromazine is able to interact with adrenochrome yielding a complex more stable than the acetylcholine-adrenochrome complex postulated as the endo-genous psychotogenic agent in mental illness. The toxicity of the acetylcholine-adrenochrome complex is related to its ability of inhibiting acetylcholinesterase and activating monoaminoxidase obtained from extracts of baboon brain.
URI
http://www.sciencedirect.com/science/article/pii/0006295272902705http://hdl.handle.net/11295/91705
Citation
Biochemical Pharmacology Volume 21, Issue 2, 15 January 1972, Pages 203–207Publisher
University of Nairobi
Collections
- Faculty of Health Sciences (FHS) [10378]