Establishing and sustaining a healthy vaginal environment:
Date
2011Author
Balkus, Jennifer E.
Richardson, Barbra A.
Mandaliya, Kishorchandra
Kiarie, James
Jaoko, Walter
Ndinya-Achola, JO
Marrazzo, Jeanne
Farquhar, Carey
McClelland, R. Scott
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
Data from a randomized trial of oral periodic presumptive
treatment (PPT) to reduce vaginal infections were analyzed
to assess the effect of the intervention on a healthy vaginal
environment (normal flora confirmed by Gram stain with no
candidiasis or trichomoniasis). The incidence of a healthy
vaginal environment was 608 cases per 100 person-years in
the intervention arm and 454 cases per 100 person-years in
the placebo arm (hazard ratio [HR], 1.36; 95% confidence
interval [CI], 1.17–1.58). Sustained vaginal health (healthy
vaginal environment for R3 consecutive visits) was also
more frequent in the intervention arm (HR, 1.69; 95% CI,
1.23–2.33). PPT is effective at establishing and sustaining
a healthy vaginal environment.
URI
http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/9877http://www.ncbi.nlm.nih.gov/pubmed/21673045
Citation
JID 2011:204Collections
- Faculty of Health Sciences (FHS) [10378]