Show simple item record

Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV Exposed, seronegative female sex workers in Kenya

dc.contributor.authorChege, Duncan
dc.contributor.authorChai, Yijie
dc.contributor.authorHuibner, Sanja
dc.contributor.authorKain, Taylor
dc.contributor.authorWachihi, Charles
dc.contributor.authorKimani, Makubo
dc.contributor.authorBarasa, Samson
dc.contributor.authorMcKinnon, Lyle R.
dc.contributor.authorMuriuki, Festus K.
dc.contributor.authorKariri, Anthony
dc.contributor.authorJaoko Walter G.
dc.contributor.authorAnzala, Omu
dc.contributor.authorKimani, Joshua
dc.contributor.authorBall, T. Blake
dc.contributor.authorPlummer, Francis A.
dc.contributor.authorKaul, Rupert
dc.date.accessioned2013-02-14T13:15:17Z
dc.date.available2013-02-14T13:15:17Z
dc.date.issued2012
dc.identifier.urihttp://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/9906
dc.description.abstractIdentifying the immune correlates of reduced susceptibility to HIV remains a key goal for the HIV vaccine field, and individuals who are HIV-exposed, seronegative (HESN) may offer important clues. Reduced systemic immune activation has been described in HESN individuals. Conversely, pro-inflammatory T cell subsets, particularly CD4+ T cells producing the cytokine IL17 (Th17 cells), may represent a highly susceptible target for HIV infection after sexual exposure. Therefore, we characterized the cellular pro-inflammatory and IL17/IL22 cytokine immune milieu in the genital mucosa and blood of HESN female sex workers (FSWs).en
dc.language.isoenen
dc.titleBlunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV Exposed, seronegative female sex workers in Kenyaen
dc.typeArticleen


Files in this item

Thumbnail
Name:
Abstract.pdf
Size:
24.18Kb
Format:
PDF
View/Open

This item appears in the following Collection(s)

Show simple item record