Browsing College of Health Sciences (CHS) by Title
Now showing items 1-20 of 44
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Adolescent experiences, perceptions, and preferences for the process of HIV status disclosure in Kenya
(University of Nairobi, 2023)Introduction: Disclosure of HIV status to adolescents living with HIV has been associated with improved treatment outcomes. However, there are limited data regarding the experiences of, perceptions of, and preferences for ... -
The African Development Corridors Database: a New Tool to Assess the Impacts of Infrastructure Investments
(University of Nairobi, 2022)The objectives of this study were to (1)explore the quality of clinical data generated from hospitals providing in-patient neonatal care participating in a clinical information network (CIN) and whether data improved over ... -
Analysis of the TCR Repertoire in HIV-Exposed but Uninfected Infants
(University of Nairobi, 2019)Maternal human immunodeficiency virus (HIV) infection has been shown to leave profound and lasting impacts on the HIV-exposed uninfected (HEU) infant, including increased mortality and morbidity, immunological changes, and ... -
Antenatal depressive symptoms in Kenyan women living with HIV: contributions of recent HIV diagnosis, stigma, and partner violence
(University of Nairobi, 2022)Depression among pregnant women living with HIV (WLWH) in sub-Saharan Africa leads to poor pregnancy and HIV outcomes. This cross-sectional analysis utilized enrollment data from a randomized trial (Mobile WAChX, NCT02400671) ... -
Assessment of independent comorbidities and comorbidity measures in predicting healthcare facility-onset Clostridioides difficile infection in Kenya
(University of Nairobi, 2022)Introduction: Clostridioides difficile is primarily associated with hospital-acquired diarrhoea. The disease burden is aggravated in patients with comorbidities due to increased likelihood of polypharmacy, extended hospital ... -
Cancer is associated with coronavirus disease (COVID-19) severity and mortality: A pooled analysis
(University of Nairobi, 2020)Background: Coronavirus disease 2019 (COVID-19) is a rapidly escalating pandemic that has spread to many parts of the world. As such, there is urgent need to identify predictors of clinical severity in COVID-19 patients. ... -
Complementary Feeding: Beyond Nutrition.
(University of Nairobi, 2018)In this article, we will summarize the key non-nutritional aspects of the introduction of complementary feeding. Intestinal maturation related to starch digestion is relatively complete by the time complementary feeding ... -
Concentrations of thiocyanate, hypothiocyanite, ‘free’ and ‘total’ lysozyme, lactoferrin and secretory lgA in resting and stimulated whole saliva of children aged 12–14 years and the relationship with plaque accumulation and gingivitis
(University of Nairobi, 1993)Resting and stimulated whole saliva was collected from 94 children aged 12–14 years and analyzed for thiocyanate, hypothiocyanite, ‘free’ and ‘total’ lysozyme, lactoferrin and secretory IgA. Clinical assessments of the ... -
Defining No and Low (NoLo) Alcohol Products
(University of Nairobi, 2022)Reducing the alcoholic strength in beverages as a strategy to reduce harmful alcohol use has been proposed by multilateral institutions such as the World Health Organization and governments worldwide. Different industrial ... -
Determinants of survival outcomes among esophageal cancer patients at a national referral hospital in Kenya
(University of Nairobi, 2022)Introduction: The overall 5-year survival rate for esophageal cancer patients in low- and middle-income countries was reported to be low, despite the availability of advanced treatments. Thus, this study aimed to assess ... -
Development of antibody-dependent cell cytotoxicity function in HIV-1 antibodies.
(University of Nairobi, 2021)A prerequisite for the design of an HIV vaccine that elicits protective antibodies is understanding the developmental pathways that result in desirable antibody features. The development of antibodies that mediate ... -
Differential Elevation of Inflammation and CD4+ T Cell Activation in Kenyan Female Sex Workers and Non-Sex Workers Using Depot-Medroxyprogesterone Acetate.
(University of Nairobi, 2021)Background Depot Medroxyprogesterone (DMPA) is one of the most widely used contraceptives in Sub-Saharan Africa where HIV incidence is high. We explored the effect of DMPA on the activation of HIV cellular targets and ... -
Drug therapy problems and health related quality of life among patients with colorectal cancer in a Kenyan tertiary health facility.
(University of Nairobi, 2021)Background: Colorectal cancer is the third most common form of cancer in males and the second in females globally. The ill-health due to cancer and use of multiple therapies may result in drug related problems and also ... -
Effect of A Natural Extract Toothpaste on the Bacteria Colonies of Initial Dental Plaque Colonizers
(University of Nairobi, 2017)To determine the effect of a natural extract toothpaste Parodontax® on the numbers of initial dental plaque colonizers. Methods: AQuasi- clinical trial type of study was conducted on 48 participants (age between 18 and ... -
Effect of umbilical cord milking versus delayed cord clamping on preterm neonates in Kenya: A randomized controlled trial.
(University of Nairobi, 2021)Background Delayed cord clamping (DCC) is a placental to new-born transfusion strategy recommended by obstetric and gynaecological societies. Though not widely adopted, umbilical cord milking (UCM) may achieve faster ... -
Efficacy of Bentonite and Fumonisin Esterase in Mitigating the Effects of Aflatoxins and Fumonisins in Two Kenyan Cattle Breeds
(University of Nairobi, 2023)The objective of the study was to investigate the efficacy of bentonite and fumonisin esterase, separately or combined, in mitigating the effects of aflatoxins (AF) and fumonisins (FUM) in Boran and Friesian-Boran crossbreed ... -
Factors associated with hospital length of stay in patients admitted with suspected malaria in Kenya: secondary analysis of a cross-sectional survey
(University of Nairobi, 2022)Objectives: To investigate factors associated with hospital length of stay (LOS) in patients admitted with suspected malaria using a competing risk approach. Setting: County government referrals and major faith-based ... -
Factors associated with use of long-acting reversible and permanent contraceptives among married women in rural Kenya: A community-based cross-sectional study in Kisii and Kilifi counties
(University of Nairobi, 2022)Long-acting and permanent contraceptive methods (LAPM) are effective and economical methods for delaying or limiting pregnancies, however they are not widely used. The Kenya government is promoting the use of modern methods ... -
Gender Norms and Family Planning Amongst Pastoralists in Kenya: a Qualitative Study in Wajir and Mandera
(University of Nairobi, 2022)There is growing recognition among global health practitioners of the importance of rights-based family planning (FP) programming that addresses inequities. Despite Kenya achieving its national FP target, inequities in ... -
High Prevalence of Multidrug-Resistant Clostridioides difficile Following Extensive Use of Antimicrobials in Hospitalized Patients in Kenya.
(University of Nairobi, 2021)Introduction Clostridioides difficile is a neglected pathogen in many African countries as it is generally not regarded as one of the major contributors toward the diarrheal disease burden in the continent. However, several ...
