Browsing Faculty of Health Sciences (FHS) by Author "Ameyaw MM."

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Ethnic Differences In Thiopurine Methyltransferase Pharmacogenetics: Evidence For Allele Specificity In Caucasian And Kenyan Subjects.

McLeod HL.; Pritchard SC.; Githang'a Jessie N.; Indalo A.; Ameyaw MM.; Powrie RH.; Booth L.; Collie-Duguid ES. (University of NairobiDepartment of Biochemistry, 1999-12)

Thiopurine methyltransferase (TPMT) degrades 6-mercaptopurine, azathioprine and 6-thioguanine which are commonly used in the treatment of autoimmune diseases, leukaemia and organ transplantation. TPMT activity is polymorphic ...