Systemic antibiotic prophylaxis in elective cesarean delivery.
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Date
1998-06Author
Rizk, DE
Nsanze, H
Mabrouk, MH
Mustafa, N
Thomas, L
Kumar, M
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
OBJECTIVE:
To test the value of using prophylactic antibiotics at elective cesarean delivery.
METHOD:
One-hundred and twenty women delivered by elective cesarean in the absence of labor and before the rupture of membranes were randomized to receive either 1.5 g of cefuroxime intravenously at cord clamping (n = 59) or no prophylaxis (control group, n = 61).
RESULTS:
Twelve women developed febrile morbidity (six study, six control, P = 0.09). Of these, five had endometritis (two study, three control, P = 0.09) and two had wound infection (one study, one control, P = 0.09). Ten more women had microbiological evidence of endometritis and wound infection (six study, four control, P = 0.08). There was no significant difference in the hospital stay (6.5 days study, 6.8 days control, P = 0.06). Staphylococcus aureus was the commonest pathogen accounting for 14 infection episodes. Amniotic fluid culture could not predict the development of infection.
CONCLUSION:
Administration of prophylactic antibiotics at elective cesarean deliveries was not associated with decreased postoperative morbidity.
URI
http://www.ncbi.nlm.nih.gov/pubmed/9688485http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/30988
Citation
nt J Gynaecol Obstet. 1998 Jun;61(3):245-51.Publisher
University of Nairobi. Department of Medicine
Collections
- Faculty of Health Sciences (FHS) [10378]