Detection Of Serum Hbv-dna By Molecular Hybridisation. Correlation With Hbeag/anti-hbe Status, Racial Origin, Liver Histology And Hepatocellular Carcinoma.
View/ Open
Date
1985Author
Karayiannis, P
Fowler, MJ
Lok, AS
Greenfield, C
Monjardino, J
Thomas, HC
Type
ArticleLanguage
enMetadata
Show full item recordAbstract
The relationship of the presence of hepatitis B virus (HBV) DNA in serum, a measure of HBV-replication, to HBeAg/anti-HBe status has been examined. In Northern Europe, there is a strong positive correlation between the presence of HBV-DNA and HBe antigenaemia and a negative correlation with the presence of anti-HBe. These associations are less marked in patients from Southern Europe, Africa, the Middle and Far East. When HBV-DNA is present in the serum of anti-HBe carriers, it is usually associated with the presence of severe liver disease or carcinoma. Forty percent of patients with hepatocellular carcinoma had evidence of continuing HBV replication.
URI
http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/2997321http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35514
Citation
J Hepatol. 1985;1(2):99-106.Publisher
University Of Nairobi Faculty Of Medicine
Collections
- Faculty of Health Sciences (FHS) [10378]