dc.contributor.author | Karayiannis, P | |
dc.contributor.author | Fowler, MJ | |
dc.contributor.author | Lok, AS | |
dc.contributor.author | Greenfield, C | |
dc.contributor.author | Monjardino, J | |
dc.contributor.author | Thomas, HC | |
dc.date.accessioned | 2013-06-18T09:50:16Z | |
dc.date.available | 2013-06-18T09:50:16Z | |
dc.date.issued | 1985 | |
dc.identifier.citation | J Hepatol. 1985;1(2):99-106. | en |
dc.identifier.uri | http://hinari-gw.who.int/whalecomwww.ncbi.nlm.nih.gov/whalecom0/pubmed/2997321 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/35514 | |
dc.description.abstract | The relationship of the presence of hepatitis B virus (HBV) DNA in serum, a measure of HBV-replication, to HBeAg/anti-HBe status has been examined. In Northern Europe, there is a strong positive correlation between the presence of HBV-DNA and HBe antigenaemia and a negative correlation with the presence of anti-HBe. These associations are less marked in patients from Southern Europe, Africa, the Middle and Far East. When HBV-DNA is present in the serum of anti-HBe carriers, it is usually associated with the presence of severe liver disease or carcinoma. Forty percent of patients with hepatocellular carcinoma had evidence of continuing HBV replication. | en |
dc.language.iso | en | en |
dc.publisher | University Of Nairobi | en |
dc.title | Detection Of Serum Hbv-dna By Molecular Hybridisation. Correlation With Hbeag/anti-hbe Status, Racial Origin, Liver Histology And Hepatocellular Carcinoma. | en |
dc.type | Article | en |
local.publisher | Faculty Of Medicine | en |