The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group.
dc.contributor.author | Brunham, RC | |
dc.contributor.author | Kimani, J | |
dc.contributor.author | Bwayo, J | |
dc.contributor.author | Maitha, G | |
dc.contributor.author | Maclean, I | |
dc.contributor.author | Yang, C | |
dc.contributor.author | Shen, C | |
dc.contributor.author | Roman, S | |
dc.contributor.author | Nagelkerke, NJ | |
dc.contributor.author | Cheang, M | |
dc.contributor.author | Plummer, FA | |
dc.date.accessioned | 2013-10-18T09:24:16Z | |
dc.date.available | 2013-10-18T09:24:16Z | |
dc.date.issued | 1996 | |
dc.identifier.uri | http://erepository.uonbi.ac.ke:8080/xmlui/handle/123456789/57721 | |
dc.identifier.uri | http://www.ncbi.nlm.nih.gov/pubmed/8603976 | |
dc.description.abstract | Female sex workers in Nairobi were prospectively evaluated for risk factors of incident Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P=.007), gonococcal infection (P=.002), human immunodeficiency virus (HIV) seropositivity (P=.003), HIV seroconversion (P=.001), and duration of prostitution (P=.002). Eighteen different C. trachomatis outer membrane protein (omp1) genotypes were identified, with the allelic composition of the C. trachomatis population changing significantly over time (P=.005). Seventeen of 19 reinfections > or = 6 months apart were with different C. trachomatis omp1 genotypes. Women with HIV infection had an increased proportion of visits with C. trachomatis infection (P=.001) and an increased risk of reinfection (P=.008). Overall, the data demonstrate significant fluctuations in the genotype composition of the C. trachomatis population and a reduced rate of same-genotype reinfection consistent with the occurrence of strain-specific immunity. | en |
dc.language.iso | en | en |
dc.publisher | University of Nairobi | en |
dc.title | The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group. | en |
dc.type | Article | en |
local.publisher | College of Health Science | en |
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