Journal Articles: Recent submissions
Now showing items 2721-2740 of 29939
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Steroid-induced impairment of glucose tolerance: Prevalence among pediatric patients on long-term steroid use in Nigeria.
(University of Nairobi, 2017)INTRODUCTION: Glucocorticoid (referred to from here on as simply steroid) is used for effective treatment of various inflammatory disorders since its discovery in 1940s. However, these useful drugs cause important side ... -
Non-communicable disease syndemics: poverty, depression, and diabetes among low-income populations.
(University of Nairobi, 2017)The co-occurrence of health burdens in transitioning populations, particularly in specific socioeconomic and cultural contexts, calls for conceptual frameworks to improve understanding of risk factors, so as to better ... -
Glucose-lowering therapies, adequacy of metabolic control, and their relationship with comorbid depression in outpatients with type 2 diabetes in a tertiary hospital in Kenya.
(University of Nairobi, 2017)BACKGROUND: Depression and diabetes mellitus are important comorbid conditions with serious health consequences. When depression and diabetes are comorbid, depression negatively affects self-management activities of ... -
Task shifting the management of non-communicable diseases to nurses in Kibera, Kenya: does it work?
(University of Nairobi, 2016)BACKGROUND: In sub-Saharan Africa there is an increasing need to leverage available health care workers to provide care for non-communicable diseases (NCDs). This study was conducted to evaluate adherence to Médecins ... -
Traditional therapies used to manage diabetes and related complications in Mauritius: a comparative Ethnoreligious study.
(University of Nairobi, 2016)Religious communities from Mauritius still rely on traditional therapies (TT) for primary healthcare. Nonetheless, there is still a dearth of scientific information on TT used by the different religious groups to manage ... -
Esophageal squamous dysplasia is common in asymptomatic Kenyans: a prospective, community-based, cross-sectional study.
(University of Nairobi, 2016)OBJECTIVES: Esophageal squamous cell carcinoma (ESCC) is endemic in east Africa and is a leading cause of cancer death among Kenyans. The asymptomatic precursor lesion of ESCC is esophageal squamous dysplasia (ESD). We ... -
Optimal Z-score use in surgical decision-making in pulmonary atresia with intact ventricular septum.
(University of Nairobi, 2017)OBJECTIVES: In the surgical treatment of pulmonary atresia with intact ventricular septum, the size of the tricuspid valve annulus (as measured by z-scores) has emerged as a significant factor in deciding which repair ... -
Consensus statement: supporting safer conception and pregnancy for men and women living with and affected by HIV
(University of Nairobi, 2017)Safer conception interventions reduce HIV incidence while supporting the reproductive goals of people living with or affected by HIV. We developed a consensus statement to address demand, summarize science, identify ... -
Safety, immunogenicity, and cross-species protection of a plasmid DNA encoding Plasmodium falciparum SERA5 polypeptide, microbial epitopes and chemokine genes in mice and olive baboons.
(University of Nairobi, 2017)Incorporation of biomolecular epitopes to malarial antigens should be explored in the development of strain-transcending malarial vaccines. The present study sought to determine safety, immunogenicity and cross-species ... -
The Highest Common Factor In The Current And Future Information Profession
(university of Nairobi, 2011)Rapid developments in ICT and globalization impinge on the traditional information profession, necessitating a paradigm shift if the profession is to stay relevant in an ever changing environment. This paper acknowledges ... -
Costs of integrating cervical cancer screening at an HIV clinic in Kenya.
(University of Nairobi, 2017)OBJECTIVE: To estimate the societal-level costs of integrating cervical cancer screening into HIV clinics in Nairobi, Kenya. METHODS: A cross-sectional micro-costing study was performed at Coptic Hope Center for ... -
Potential biomarkers associated with discrimination between latent and active pulmonary tuberculosis.
(University of Nairobi, 2017)SETTING: A third of the world's population has latent tuberculous infection (LTBI). Current TB diagnostics used in developing countries are ineffective and are unable to distinguish LTBI from active TB. Identifying ... -
Knowledge, attitudes and practices towards spotted fever group rickettsioses and q fever in Laikipia and Maasai Mara, Kenya.
(University of Nairobi, 2016)Many factors contribute to misdiagnosis and underreporting of infectious zoonotic diseases in most sub-Saharan Africa including limited diagnostic capacity and poor knowledge. We assessed the knowledge, practices and ... -
Simplified paper format for detecting HIV drug resistance in clinical specimens by oligonucleotide ligation.
(University of Nairobi, 2016)Human immunodeficiency virus (HIV) is a chronic infection that can be managed by antiretroviral treatment (ART). However, periods of suboptimal viral suppression during lifelong ART can select for HIV drug resistant (DR) ... -
Reversibility of glomerular renal function decline in hiv-uninfected men and women discontinuing emtricitabine-tenofovir disoproxil fumarate pre-exposure prophylaxis.
(University of Nairobi, 2016)BACKGROUND: Tenofovir disoproxil fumarate (TDF) pre-exposure prophylaxis (PrEP) use is associated with a small but statistically significant decline in estimated glomerular filtration rate (eGFR). We investigated the ... -
Low risk of proximal tubular dysfunction associated with emtricitabine-tenofovir disoproxil fumarate preexposure prophylaxis in men and women.
(University of Nairobi, 2016)OBJECTIVE: Tenofovir disoproxil fumarate (TDF) is associated with proximal tubular dysfunction (tubulopathy) when used in the treatment of human immunodeficiency virus (HIV) infection. We evaluated whether TDF causes ... -
Modeling the Cost-Effectiveness of Home-Based HIV Testing and Education (HOPE) for Pregnant Women and Their Male Partners in Nyanza Province, Kenya.
(University of Nairobi, 2016)INTRODUCTION: Women in sub-Saharan Africa face a 2-fold higher risk of HIV acquisition during pregnancy and postpartum and the majority do not know the HIV status of their male partner. Home-based couple HIV testing for ... -
Brief Report: Sexual Violence Against HIV-Positive Women in the Nyanza Region of Kenya: Is Condom Negotiation an Instigator?
(University of Nairobi, 2017)For people living with HIV, exposure to sexual violence (SV) is associated with decreased adherence to antiretroviral medication, a primary predictor of their survival. Identification of risk factors for SV is a pressing ... -
Time to act-comprehensive abortion care in east Africa.
(University of Nairobi, 2016) -
Risk factors for hypoxia and tachypnea among adolescents with vertically-acquired HIV in Nairobi.
(University of Nairobi, 2017)BACKGROUND: Chronic lung diseases are increasingly recognized complications of vertically-acquired HIV among adolescents in sub-Saharan Africa and may manifest with hypoxia or tachypnea. We sought to determine the ...
