Journal Articles: Recent submissions
Now showing items 8241-8260 of 29992
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Health system challenges to integration of mental health delivery in primary care in Kenya- perspectives of primary care health workers.
(University of NairobiSchool of Medicine, 2013-09)BACKGROUND: Health system weaknesses in Africa are broadly well known, constraining progress on reducing the burden of both communicable and non-communicable disease (Afr Health Monitor, Special issue, 2011, 14-24), and ... -
Severe acute respiratory syndrome-related coronavirus is inhibited by interferon- alpha
(University of NairobiDepartment of Medical Microbiology, University of Manitoba,, 2004-04)Current treatment schemes for severe acute respiratory syndrome (SARS) include broad-spectrum antibiotics, glucocorticoids, and ribavirin. We evaluated the susceptibility of the SARS-related coronavirus (SARS CoV) to ... -
Short structured general mental health in service training programme in Kenya improves patient health and social outcomes but not detection of mental health problems - a pragmatic cluster randomised controlled trial.
(University of NairobiSchool of Medicine, 2013-11)Trial design: A pragmatic cluster randomised controlled trial. METHODS: Participants: Clusters were primary health care clinics on the Ministry of Health list. Clients were eligible if they were aged 18 and over. ... -
Analysis of multimerization of the SARS coronavirus nucleocapsid protein
(University of NairobiNational Microbiology Laboratory, Health Canada, 2004-04)Severe Acute Respiratory Syndrome (SARS), an emerging disease characterized by atypical pneumonia, has recently been attributed to a novel coronavirus. The genome of SARS Coronavirus (SARS-CoV) has recently been sequenced, ... -
Dilated cardiomyopathy and myocarditis in Kenya: an endomyocardial biopsy study.
(University of NairobiSchool of Medicine, 1993-09)We have studied, by light and electron microscopy, left ventricular endomyocardial biopsy specimens from 18 African patients (14 men) with idiopathic dilated cardiomyopathy in Nairobi. Nine patients (50%) had evidence of ... -
Mechanisms of CD4+ T lymphocyte cell death in human immunodeficiency virus infection and AIDS.
(University of NairobiDepartment of Medical Microbiology, 2003-07)AIDS, caused by the retroviruses human immunodeficiency virus type 1 and type 2 (HIV-1 and HIV-2), has reached pandemic proportions. Therefore, it is critical to understand how HIV causes AIDS so that appropriate therapies ... -
A survey on management perspectives of the state of workplace health and safety practices in Kenya.
(University of NairobiSchool of Medicine, 1999-07)A baseline survey was conducted in 1995 on management perspectives of occupational health and safety (OHS) structures and practices in Kenya. This was achieved by interviewing management and supervisory staff attending 1 ... -
Development and characterisation of neutralising monoclonal antibody to the SARS-coronavirus.
(University of NairobiNational Centre for Foreign Animal Disease, CFIA, Winnipeg, Canada, 2004-09)There is a global need to elucidate protective antigens expressed by the SARS-coronavirus (SARS-CoV). Monoclonal antibody reagents that recognise specific antigens on SARS-CoV are needed urgently. In this report, the ... -
La mancanza di coordinamento e armonizzazione negli interventi dei donatori per la risposta all'HIV e AIDS in Kenya: descrizione del problema
(College of Humanities and Social Sciences, 2005)Le ONG che operano sotto I'ombrello dell'Osservatorio Italiano per l'Azione Globale contro I'AIDS notano con preoccupazione la mancanza di coordinamento tra i diversi progetti per la lotta all'HIV e AIDS finanziati dai ... -
QUASI analysis of the HIV-1 envelope sequences in the Los Alamos National Laboratory HIV sequence database: pattern and distribution of positive selection sites and their frequencies over years
(University of NairobiDepartment of Medical Microbiology, 2007-04)The envelope (env) protein of human immunodeficiency virus type 1 (HIV-1) plays a crucial role in virus entry and is a central target for HIV vaccine design. Using the QUASI program, we analyzed the conserved regions of ... -
Gender -Specific Constraints Affecting Technology use and Household Food Security in Western Province of Kenya
(College of Humanities and Social Sciences, 2010) -
Low vitamin B12 intake during pregnancy and lactation and low breastmilk vitamin 12 content in rural Kenyan women consuming predominantly maize diets.
(Department of Community Health Sciences, UCLA Fielding School of Public Health,, 2013)BACKGROUND: Vitamin B12 deficiency during pregnancy and lactation may negatively affect fetal growth, brain development, pregnancy outcome, and breastmilk vitamin B12 content. OBJECTIVE: To examine associations ... -
Animal source foods have a positive impact on the primary school test scores of Kenyan schoolchildren in a cluster-randomised, controlled feeding intervention trial.
(CambridgeDepartment of Community Health Sciences, Jonathan and Karin Fielding School of Public Health, University of California, Los Angeles, 2013)Micronutrient deficiencies and suboptimal energy intake are widespread in rural Kenya, with detrimental effects on child growth and development. Sporadic school feeding programmes rarely include animal source foods (ASF). ... -
Integration of family planning services into HIV care and treatment in Kenya: a cluster-randomized trial.
(Kenya Medical Research Institute, Kisumu, KenyaDepartment of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, USACenter for AIDS Prevention, Department of Medicine, University of California, San Francisco, USA., 2013)OBJECTIVE: To determine whether integrating family planning services into HIV care is associated with increased use of more effective contraceptive methods (sterilization, intrauterine device, implant, injectable or ... -
Cost, cost-efficiency and cost-effectiveness of integrated family planning and HIV services.
(Wolters KluwerCenter for AIDS Prevention Studies, Department of Medicine, University of California,Kenya Medical Research Institute, Nairobi,, 2013)OBJECTIVE: To evaluate costs, cost-efficiency and cost-effectiveness of integration of family planning into HIV services. INTERVENTION: Integration of family planning services into HIV care and treatment ... -
Across-sectional survey of prevalence and correlates of couple sexual concurrency among married couples in fishing communities along Lake Victoria in Kisumu, Kenya.
(BMJCenter for Microbiology Research, Kenya Medical Research Institute, Kisumu, Kenya.College of Health Sciences, University of Nairobi, 2013)OBJECTIVE: Sexual concurrency has been associated with HIV infection. Since HIV in sub-Saharan Africa is mostly spread within the context of heterosexual couples, it is necessary that intervention is focused on such ... -
Responses to and Resources for Intimate Partner Violence: Qualitative Findings From Women, Men, and Service Providers in Rural Kenya.
(Sage PublicationsCollege of Health Sciences, University of Nairobi, 2013)Intimate partner violence (IPV) is reported by one in three women globally, but the prevalence is much higher in East Africa. Though some formal and informal resources do exist for women experiencing IPV, data suggest that ... -
Immune Quiescence: a model of protection against HIV infection
(2013-11-20)Abstract Aberrant immune activation is a strong correlate of HIV disease progression, but little is known about how immune activation alters susceptibility to HIV infection. Susceptibility to HIV infection varies between ... -
Pyrosequencing of the chaperonin-60 universal target as a tool for determining microbial community composition.
(University of NairobiDepartment of Medical Microbiology University of Manitoba, 2009-05)We compared dideoxy sequencing of cloned chaperonin-60 universal target (cpn60 UT) amplicons to pyrosequencing of amplicons derived from vaginal microbial communities. In samples pooled from a number of individuals, the ... -
A comparative analysis of gene expression patterns and cell phenotypes between cervical and peripheral blood mononuclear cells.
(University of NairobiDepartment of Medical Microbiology,, 2009-12)Studies of the immunological environment in the female genital tract (FGT) are critical for the development of vaccines or microbicides to halt the spread of sexually transmitted infections. Challenges arise due to the ...
