Journal Articles: Recent submissions
Now showing items 8261-8280 of 29992
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Systems biology-based approaches to understand HIV-exposed uninfected women.
(University of NairobiPublic Health Agency of Canada,, 2010-05)Worldwide HIV infects women more frequently than men, and it is clear that not all exposed to HIV become infected. Several populations of HIV-exposed uninfected (EU) women have been identified, including discordant couples ... -
The Earth Charter in Higher Education for Sustainability
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 2009)A central challenge of sustainable development is to provide material sufficiency for the human population while preserving the integrity of Earth’s biosphere. Current modes of economic production and consumption accomplish ... -
Unbiased proteomics analysis demonstrates significant variability in mucosal immune factor expression depending on the site and method of collection.
(University of NairobiDepartment of Medical Microbiology, 2013-11)Female genital tract secretions are commonly sampled by lavage of the ectocervix and vaginal vault or via a sponge inserted into the endocervix for evaluating inflammation status and immune factors critical for HIV microbicide ... -
Identification of three novel human leukocyte antigen alleles, HLA-B58:43 HLA-C03:190 and HLA-DPA101:12 in an East African cohort.
(University of NairobiHIV and Human Genetics, National Microbiology Laboratory, 2013-08)Three novel human leukocyte antigen (HLA) alleles were identified using a sequence-based typing of HLA class I and class II alleles of 1867 participants from a male circumcision cohort in Kenya. The new alleles were first ... -
Factors Affecting Implementation of Strategic Plans in Ministries in Kenya: A Case of Ministry of Housing
(University of NairobiDepartment of Real Estate and Construction Management, 2013)Strategy is the heart of strategic management because it helps an organization to plan, formulate and implement various tasks in its attempts to prosper. Strategic planning relates to the distinct elements which differ ... -
High pH reversed-phase chromatography as a superior fractionation scheme compared to off-gel isoelectric focusing for complex proteome analysis
(University of NairobiDepartment of Medical Microbiology, 2013-10)MS/MS is the technology of choice for analyzing complex protein mixtures. However, due to the intrinsic complexity and dynamic range present in higher eukaryotic proteomes, prefractionation is an important step to maximize ... -
HIV and Interferon Regulatory Factor 1: A Story of Manipulation and Control.
(University of NairobiDepartment of Medical Microbiology,, 2013-11)Members of the interferon regulatory factor (IRF) family control the expression of numerous proteins, many of which are central to regulating host immune responses. IRF1 is one of the central mediators of the innate and ... -
Validation of a modified version of the PRIME screen for psychosis-risk symptoms in a non-clinical Kenyan youth sample.
(ElsevierCollege of Health Sciences, 2013)The PRIME screen is a self-administered questionnaire designed to quickly assess individuals at risk for developing a psychotic disorder. It is shorter in both length and administration time compared to the Structured ... -
Anti-HIV-1 activity of elafin depends on its nuclear localization and altered innate immune activation in female genital epithelial cells.
(University of NairobiSchool of Medicine, 2012-12-27)Elafin (E) and its precursor trappin-2 (Tr) are alarm antiproteases with antimicrobial and immunomodulatory activities. Tr and E (Tr/E) have been associated with HIV-1 resistance. We recently showed that Tr/E reduced IL-8 ... -
Environmental education in North America: alternative perspectives
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 1996) -
Plasma and mucosal fluid from HIV type 1-infected patients but not from HIV type 1-exposed uninfected subjects prevent HIV type 1-exposed DC from infecting other target cells.
(University of NairobiDepartment of Medical Microbiology, 2007-01-23)Highly exposed persistently seronegative (HEPS) individuals have previously been shown to mount HIV-1-specific humoral and cellular immune responses in the mucosa, despite their uninfected status. It is thus possible that ... -
Acting locally: innate mucosal immunity in resistance to HIV-1 infection in Kenyan commercial sex workers
(University of NairobiDepartment of Medical Microbiology, 2013-06-26)Cohort studies of female commercial sex workers (CSWs) in Kenya were among the first to identify highly HIV-1-exposed seronegative (HESN) individuals. As natural resistance is usually mediated by innate immune mechanisms, ... -
What If? The Educational Possibilities of the Earth Charter
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 2004)Evoking a concern for intergenerational equity and claiming that the bounty and beauty of Earth have become diminishing prospects, I introduce the Earth Charter as an expression of the hopes of diverse communities around ... -
The Promise of Sustainability in Higher Education: A Synthesis
(Kluver Academic PublishersThe Wangari Maathai Institute for Peace and Environmental Studies, 2004) -
The Problematics of Sustainability in Higher Education: A Synthesis
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 2004) -
Learning for a Sustainable Environment: professional development and teacher education in environmental education in the Asia‐Pacific region
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 1996)The close link between environmental education and development education advocated by major international reports of the last decade is operant in the UNESCO Asia‐Pacific region. A regional collaborative effort sponsored ... -
The Effect of foreign exchange rate fluctuation on the financial performance of listed companies in Kenya
(School of Business, 2013)This study developed a model of foreign exchange exposure dependent on three variables, the firm‘s imports, exports and their effect on profits formulating the problem statement of the effects (if any) that variations ... -
Introduction: higher education for sustainable development
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 2002)Over the past 30 years, the global community has been debating the signi(cance of environmental problems and the meaning and urgency of sustainable development. The major purpose of the World Summit on Sustainable ... -
Formative Influences in the Lives of Environmental Educators in the United States
(University of NairobiThe Wangari Maathai Institute for Peace and Environmental Studies, 1999)The author obtained autobiographical statements and other data from 510 US members of the North American Association for Environmental Education. This report (1) presents findings regarding human and vicarious influences ... -
Factors Influencing Non-payment Of Water Bills By Embu Municipality Residents, Embu County, Kenya
(University of NairobiSchool of Education, 2013)Non-payment or delays in payments of water bills by customers to Water Service Providers (WSPs) resulting to decline in revenues, for water supplied to them has been cited as a major concern for sustainable, effective ...
