Journal Articles: Recent submissions
Now showing items 8561-8580 of 29992
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Delaying Sexual Debut As A Strategy For Reducing Hiv Epidemic In Kenya.
(University of NairobiVeterinary Anatomy and Physiology, 2013-06-17)The study purpose was to determine the association between sexual debut and HIV sero-status, and factors contributing to a positive HIV sero-status. Retrospective cross-sectional data from the Kenya Demographic and Health ... -
Malignant lymphoma in Kenya: Pattern and pathology (excluding Burkitt's lymphoma).
(University of Nairobi,College of health sciences,, 1977-09) -
Marital Status And Risk Of Hiv Infection In Slum Settlements Of Nairobi, Kenya: Results From A Cross-sectional Survey.
(University of NairobiAfrican Population and Health Research Center., 2013-03-17)Kenya still faces major challenges due to the HIV/AIDS epidemic. This study examined the association between marital status and risk of HIV infection in urban slums of Nairobi. Data were derived from a cross-sectional ... -
Studies on schistosomiasis in western Kenya: I. Evidence for immune-facilitated excretion of schistosome eggs from patients with Schistosoma mansoni and human immunodeficiency virus coinfections
(University of Nairobi,Center for HIV prevention and Research, 1997-05)Persons employed as vehicle washers in the town of Kisumu, Kenya are exposed for several hours each day to water in Lake Victoria that contains Schistosoma mansoni-infected Biomphalaria pherifferi snails. This results in ... -
Mucosal and plasma IgA from HIV-exposed seronegative individuals neutralize a primary HIV-1 isolate.
(University of NairobiCollege of Health Science, 2000)Abstract OBJECTIVE: To characterize functional properties of HIV-specific IgA in samples representing both systemic and mucosal compartments of HIV-1 highly exposed persistently seronegative (HEPS) individuals. METH ... -
Skeletal neuromuscular and smooth muscle effects of whole venom of the green mamba, Dendroaspis angusticeps - I.
(1981)Dendroaspis angusticeps venom (75 micrograms/ml) caused an irreversible blockade of the directly as well as directly evoked contractions of the rat hemidiaphragm and indirectly evoked contractions of the chick biventer ... -
Rural culture and the conservation of Mackinders eagle owls (Bubo capensis mackinderi) in Kenya.
(University of NairobiDepartment of Zoology, 2008)The author describes her fieldwork studying a population of Mackinders eagle owls that live adjacent to small-scale farms in rural Kenya. Her study investigated the effects of farming practices on the diet and breeding ... -
The effect of treatment of schistosomiasis on blood plasma HIV-1 RNA concentration in coinfected individuals.
(University of NairobiCollege of Health Science, 2000)Abstract OBJECTIVE: To determine whether drug treatment of Schistosomiasis mansoni infection leads to a reduction in plasma HIV-1 RNA concentration in coinfected individuals. METHODS: Stool and plasma samples were ... -
Spontaneous occurrence of leptomonads in human bone marrow aspirate - case report.
(University of NairobiCollege of Health Science, 1983-04) -
Cellular immune responses of schistosomiasis patients are altered by human immunodeficiency virus type 1 coinfection.
(University of NairobiCollege of Health Science, 2001)In vitro studies suggest that CD4(+) cells with a T helper 2 (Th2) phenotype better support human immunodeficiency virus type 1 (HIV-1) replication than do cells of the Th1 phenotype. As a result, Th2-type immune responses ... -
Resistance to reinfection with Schistosoma mansoni in occupationally exposed adults and effect of HIV-1 co-infection on susceptibility to schistosomiasis: a longitudinal study.
(University of NairobiCollege of Health Science, 2002)Abstract BACKGROUND: Previous studies have reported age-dependent development of resistance to reinfection by schistosomes and identified immunological correlates of this resistance. However, whether resistance exists ... -
Increased density of human immunodeficiency virus type 1 coreceptors CCR5 and CXCR4 on the surfaces of CD4(+) T cells and monocytes of patients with Schistosoma mansoni infection..
(University of NairobiCollege of Health Science, 2003)Abstract Distribution of chemokine receptors CCR5 and CXCR4, which are also coreceptors for human immunodeficiency virus type 1 invasion of cells, was measured on the surfaces of CD4(+) T cells and monocytes in peripheral ... -
Geographic distribution of schistosomiasis and soil-transmitted helminths in Western Kenya: implications for anthelminthic mass treatment., , , , , ,.
(University of NairobiCollege of Health Science, 2003)Abstract A survey of 1,246 children 10-12 years old in 32 primary schools in Kenya near Lake Victoria was conducted to determine prevalence and distribution of schistosome and geohelminth infections. Stool and urine ... -
Studies on schistosomiasis in western Kenya: II. Efficacy of praziquantel for treatment of schistosomiasis in persons coinfected with human immunodeficiency virus-1
(University of Nairobi,Centre for HIV prevention and research, 1998-08)Praziquantel is the drug of choice for schistosomiasis chemotherapy. Although the exact mechanism of how praziquantel kills schistosomes remains poorly understood, the immune response of the host is an important factor in ... -
Interactions between schistosomiasis and human immunodeficiency virus in Western Kenya
(University of NairobiCollege of Health Science, 2004)Abstract For the past ten years, we have been exploring the relationship between schistosomiasis and human immunodeficiency virus (HIV-1) and how coinfection with both agents may affect the pathology and progression of ... -
Short report: Evaluation of hepatic fibrosis in persons co-infected with Schistosoma mansoni and human immunodeficiency virus 1. , ,, , , .
(University of NairobiCollege of Health Science, 2004)Abstract To investigate whether infection with human immunodeficiency virus 1 (HIV-1) affects fibrosis development in patients infected with Schistosoma mansoni, we evaluated schistosomiasis-induced pathology in the ... -
Short report: Childhood coinfections with plasmodium falciparum and Scistosoma mansoni result in lower percentages of activated T cells and T regulatory memory cells than Schistosomiasis only
(University of NairobiSchool of Public Health, 2009-08)Flow cytometric analyses were performed to evaluate HLA-DR (+) activated T lymphocytes (Tact; CD3 (+)/CD4 (+)/CD25(medium)) and T regulatory cells (Treg; CD3 (+)/CD4(+)/CD25(high)) in the circulation of children 8-10 years ... -
Correlation between eosinophils and protection against reinfection with Schistosoma mansoni and the effect of human immunodeficiency virus type 1 coinfection in humans.
(University of NairobiCollege of Health Science, 2006-04)Longitudinal investigations of an adult male population of Kenyan car washers who have heavy and quantifiable occupational exposure to Schistosoma mansoni cercariae revealed that some individuals develop resistance to ... -
Higher percentages of circulating mast cell precursors correlate with susceptibility to reinfection with Schistosoma mansoni.
(University of NairobiCollege of Health Sciences, 2006-12)A high level of serum IgE is generally associated with human resistance to schistosomes, though the protective mechanisms of IgE remain undefined. We recently reported that whereas some individuals who are occupationally ... -
T regulatory cell levels decrease in people infected with Schistosoma mansoni on effective treatment.
(University of NairobiCollege of Health Science, 2007-10)Schistosomiasis mansoni is usually a chronic infection that leads to long-term, systemic exposure to schistosome antigens. Experimental Schistosoma mansoni infection is associated with immunoregulatory mechanisms, including ...
