Journal Articles: Recent submissions
Now showing items 8581-8600 of 29992
-
Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoni
(University of NairobiCollege of Health Science, 2009-08)BACKGROUND: The near exclusive use of praziquantel (PZQ) for treatment of human schistosomiasis has raised concerns about the possible emergence of drug-resistant schistosomes. METHODOLOGY/PRINCIPAL FINDINGS: We measured ... -
Human papillomavirus infection and cervical abnormalities in Nairobi, Kenya, an area with a high prevalence of human immunodeficiency virus infection.
(University of NairobiCollege of Health Science, 2008-05)Human papillomavirus (HPV) infection and cervical abnormalities, and their association with human immunodeficiency virus (HIV) infection were studied in 488 women who visited a health center in Nairobi. PCR-based HPV and ... -
The application of bovine brain microvessel endothelial-cell monolayers grown onto polycarbonate membranes in vitro to estimate the potential permeability of solutes through the blood-brain barrier
(1989)Previously our laboratory (Rim et al., Int. J. Pharm. 32:79-84. 1986) described an in vitro blood-brain barrier (BBB) model consisting of cultured bovine brain microvessel endothelial cells (BMECs) grown onto regenerated ... -
Influence of exposure history o the immunology and development of resistance to human Schistosomiasis mansoni
(University of NairobiCollege of Health Science, 2010-03)BACKGROUND: Previous studies suggest that humans can acquire immunity to reinfection with schistosomes, most probably due to immunologic mechanisms acquired after exposure to dying schistosome worms. METHODOLOGY/PRINCIPAL ... -
The life history and in vivo culture of Coelomomyces utahensis (Blastocladiomycetes).
(University of NairobiCollege of Health Science, 2009-01)Coelomomyces utahensis is a fungal parasite of several genera of mosquitoes that inhabit rock-pools in southern Utah. Studies of the biology of Coelomomyces and their potential use in biological control of mosquitoes have ... -
Effect of induction-delivery and uterine-delivery on apgar scoring of the newborn
(1991)Very short or prolonged induction-delivery interval (i.e. less than 5 minutes or more than 15 minutes) and uterine-delivery interval of more than 90 seconds has a definite effect on the apgar scoring of a newborn especially ... -
Circulating CD23+ B cell subset correlates with the development of resistance to Schistosoma mansoni reinfection in occupationally exposed adults who have undergone multiple treatments.
(University of NairobiCollege of Health Science, 2009-01)BACKGROUND: Elevated immunoglobulin E (IgE) levels are often associated with resistance to reinfection in human schistosomiasis. However, Although B cells are the source of schistosome-specific IgE, little is known about ... -
Increases in levels of schistosome-specific immunoglobulin E and CD23 (+) B cells in a cohort of Kenyan children undergoing repeated treatment and reinfection with schistosoma mansoni.
(University of NairobiCollege of Health Science, 2010-08)BACKGROUND: Age prevalence curves for areas in which schistosomiasis is endemic suggest that humans develop partial immunity to reinfection beginning in early adolescence. We conducted a 2-year longitudinal study to ... -
Outcome and haemato-toxicity of two chemotherapy regimens for childhood non-Hodgkin's lymphoma in a Kenyan hospital
(Department of Paediatrics, College of Health Sciences, University of Nairobi., 2009)BACKGROUND: Effectiveness and toxicity of childhood cancer treatments have never been evaluated in Kenya since introduction of structured care in the early seventies. OBJECTIVE: To evaluate effectiveness and ... -
Evaluation of urine CCA assays for detection for detection of Schistosoma mansoni infection in Western Kenya
(University of NairobiCollege of Health Science, 2011-01)Although accurate assessment of the prevalence of Schistosoma mansoni is important for the design and evaluation of control programs, the most widely used tools for diagnosis are limited by suboptimal sensitivity, slow ... -
Association of the gene polymorphisms IFN-gamma +874, IL-13 -1055 and IL-4 -590 with patterns of reinfection with Schistosoma mansoni.
(University of NairobiCollege of Health Science, 2009)BACKGROUND: The immunologic findings that most consistently correlate with resistance in human schistosomiasis are high levels of IgE and low levels of IgG4. We have genotyped gene and promoter polymorphisms of cytokines ... -
A comparison of the effect on gastric emptying of alfentanil or morphine given during anaesthesia for minor surgery.
(1994)Twenty patients, scheduled for minor gynaecological surgery, were studied. Anaesthesia was induced with propofol and maintained with oxygen, nitrous oxide and enflurane. Patients were randomly allocated to two groups: group ... -
Identification of cytokeratin 18 as a biomarker of mouse and human hepatosplenic schistosomiasis.
(University of NairobiCollege of Health Science, 2011-02)Previously, we demonstrated unique protein expression patterns in 20-week-Schistosoma mansoni-infected CBA/J mice with moderate splenomegaly syndrome (MSS) or hypersplemomegaly syndrome (HSS). To better understand the ... -
The hyperimmunoglobulin E syndrome--a neutrophil chemotactic defect reversible by histamine H2 receptor blockade?
(College of Health Sciences, University of Nairobi, 1980) -
Right atrial electrocardiography: a technique for the placement of central venous catheters for chemotherapy or intravenous nutrition
(1994)Central venous catheters used for chemotherapy are usually sited so that the catheter tip lies in the superior vena cava. This study evaluated right atrial electrocardiography as a method of accurately placing the catheter ... -
Schistosomiasis among young children in Usoma, Kenya
(University of NairobiCollege of Health Science, 2011-05)Although schistosomiasis burden is greatest among school-age children (SAC) (6-15 years of age), infection among preschool-age children (PSAC) (1-5 years), may be underestimated in endemic areas. We conducted a cross-sectional ... -
Geographical distribution of schistosomiasis and soil-transmitted helminths among school children in informal settlements in Kisumu City, Western Kenya.
(University of NairobiSchool of Public Health, 2011-10)This cross-sectional study determined the prevalence and distribution of schistosome and soil-transmitted helminth (STH) infections among 1,308 children aged 10-18 years in 34 primary schools in 8 informal urban settlements ... -
Practical therapeutics: psychotherapy.
(KMADepartment of Pyschiatry, 1984) -
You cannot prevent a disease; you only treat diseases when they occur: knowledge, attitudes and practices to water-health in a rural Kenyan community.
(University of NairobiSchool of Public HealthSchool of Public Health, 2011-06)OBJECTIVE: Almost 1 billion individuals lack access to improved water supplies, with 2.6 billion lacking adequate sanitation. This leads to the propagation of multiple waterborne diseases. The objective of this study was ...
