Faculty of Health Sciences (FHS): Recent submissions
Now showing items 10341-10360 of 10418
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Standardization of cytokine flow cytometry assays
(2005-06)Background: Cytokine flow cytometry (CFC) or intracellular cytokine staining (ICS) can quantitate antigen-specific T cell responses in settings such as experimental vaccination. Standardization of ICS among laboratories ... -
Substance Abuse in Outpatients Attending Rural and Urban Health Centres in Kenya
(Department of Psychiatry, College of Health Sciences, University of Nairobi,, 2000-11)OBJECTIVES: To estimate the prevalence and pattern of substance use among patients attending primary health centres in urban and rural areas of Kenya. DESIGN: A descriptive cross-sectional prevalence survey. SETTING: Urban ... -
Rapid assessment of cataract surgical services in Embu district, Kenya
(Department of Ophthalmology, School of Medicine, College of Health Sciences, University Of Nairobi, 2007)Objectives: To conduct a rapid assessment of cataract surgical services in Embu District. Design: Community based survey Setting: Embu district of the Eastern Province of Kenya Subjects: 85 clusters selected by systematic ... -
Trachoma control using the who adopted “safe with azithromycin”
(Department of Ophthalmology, School of Medicine, College of Health Sciences, University Of Nairobi, 2007)Objective: To report on and share the experiences, accomplishments and lessons learnt by African Medical and Research Foundation (AMREF), Sight Savers International (SSI), University of Nairobi (UON) and the Ministry of ... -
Immunoepidemiology of Wuchereria bancrofti Infection:
(2007)We compared the age profiles of infection and specific antibody intensities in two communities with different transmission levels in East Africa to examine the contribution of humoral responses to human immunity to ... -
Traumatic grief in Kenyan bereaved parents following the Kyanguli School fire tragedy
(1 Department of Psychiatry, University of Nairobi,2 African Medical Research Foundation, 2004-02)Following the death of 67 boys in a fire tragedy at Kyanguli School in rural Kenya, the level of traumatic grief was assessed in a sample of 164 parents and guardians whose sons died in the fire. The study was cross-sectional. ... -
Filarial-specific antibody response in East African bancroftian filariasis
(2006)The effect of host infection, chronic clinical disease, and transmission intensity on the patterns of specific antibody responses in Bancroftian filariasis was assessed by analyzing specific IgG1, IgG2, IgG3, IgG4, and ... -
Height as proxy for weight in mass azithromycin dosing of Kenyan children with active trachoma
(2008)Objectives: To determine whether height can be used as an alternative to weight in mass treatment of children aged 1-15 years with active trachoma using azithromycin and propose a height-based dose stick for Kenyan ... -
A simple and quick method for enhanced detection of specific IgE in serum from lymphatic filariasis patients
(2001)A new simple and quick technique, using a suspension of protein A agarose beads to absorb IgG4 from sera prior to determination of filarial-specific IgE in ELISA, is presented. The optimal ratio between serum and absorbant ... -
Elevated elafin/trappin-2 in the female genital tract is associated with protection against HIV acquisition
(2009)Globally, heterosexual intercourse is the primary route of HIV-1 (HIV) transmission. It follows that mechanisms that protect against HIV infection are likely operative at the genital mucosa. In HIV-resistant Kenyan sex ... -
Cervical HIV-specific IgA in a population of commercial sex workers correlates with repeated exposure but not resistance to HIV
(2009)We conducted a comprehensive cross-sectional analysis of total and HIV-specific cervical antibody levels in HIV- 1-resistant, uninfected, and infected women in order to examine the role of HIV-specific antibody responses ... -
Associations between intravaginal practices and bacterial vaginosis in Kenyan female sex workers without symptoms of vaginal infections
(2007)Bacterial vaginosis (BV) is highly prevalent among African women and has been associated with adverse pregnancy outcomes, sexually transmitted diseases, and HIV-1. GOAL: The goal of this study was to analyze the ... -
Serologic testing algorithm for recent HIV Seroconversion in estimating incidence of HIV-1 among adults visiting a VCT centre at a Kenyan tertiary health institution
(2009-05)Objective: To determine HIV high risk groups among adults visiting Kenyatta National Hospital Voluntary Counselling and Testing Centre by use of Serologic Testing Algorithm for Recent HIV Seroconversion (STARHS). Design: ... -
Psychiatric morbidity among HIV -infected children and adolescents in a resource-poor Kenyan urban community
(RoutledgeDepartment of Psychiatry , University of NairobiDepartment of Mental Health, School of Medicine, Moi University , Eldoret, 2012)The course of HIV/AIDS in children has been transformed from an acute to a chronic one with the advent of Anti-Retroviral Therapy. The aim of this study was to determine the prevalence and pattern of psychiatric morbidity ... -
The Prevalence of Depression among Family Caregivers of Children with Intellectual Disability in a Rural Setting in Kenya
(1 Department of Psychiatry, University of Nairobi,Department of Psychiatry, University of Nairobi and Africa Mental Health Foundation, 2011)Caregivers of children with intellectual disability have a great responsibility that may be stressful. The psychological well-being of the care giver may affect the quality of care given to children with intellectual ... -
Safety and Adherence to Intermittent Pre-Exposure Prophylaxis (PrEP) for HIV-1 in African Men Who Have Sex with Men and Female Sex Workers
(4/12/2012)Background: Little is known about safety of and adherence to intermittent HIV PrEP regimens, which may be more feasible than daily dosing in some settings. We present safety and adherence data from the first trial of an ... -
Antiretroviral adherence and development of drug resistance are the strongest predictors of genital HIV-1 shedding among women initiating treatment
(2010)Persistent genital human immunodeficiency virus type 1 (HIV-1) shedding among women receiving antiretroviral therapy (ART) may present a transmission risk. We investigated the associations between genital HIV-1 ... -
Eye diseases in a high HIV-risk group; the Majengo commercial sex workers in Nairobi, Kenya
(Department of Ophthalmology, School of Medicine, College of Health Sciences, University Of Nairobi, 2007)Objective: To determine the prevalence and magnitude of eye disease in a group at high risk for HIV: the Majengo commercial sex worker (CSW) cohort and see how it differs from the general population. Design: Cross sectional ... -
Reasons for Ineligibility in Phase 1 and 2A HIV Vaccine Clinical Trials at Kenya Aids Vaccine Initiative (KAVI), Kenya
(1/21/2011)Background: With the persistent challenges towards controlling the HIV epidemic, there is an ongoing need for research into HIV vaccines and drugs. Sub-Saharan African countries - worst affected by the HIV pandemic - have ... -
Efficacy of topical prednisolone phosphate 1% eye drops in reducing recurrences after bare sclera pterygium surgery
(Department of Ophthalmology, School of Medicine, College of Health Sciences, University Of Nairobi, 2007)Aim: To evaluate the efficacy of topical prednisolone phosphate 1% eye drops in reducing recurrences after bare sclera pterygium surgery. Design: Randomized controlled clinical trial. Setting: Kenyatta, Nakuru, Embu, ...
