Faculty of Health Sciences (FHS): Recent submissions
Now showing items 10321-10340 of 10418
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Prevalence and correlates of genital Warts in Kenyan female sex workers
(2012)BACKGROUND: Our goal in the present study was to investigate the prevalence and correlates of genital warts in a population of female sex workers in Mombasa, Kenya. Because of the high prevalence of human immunodeficiency ... -
HIV viral set point and host immune control in individuals with HIV-specific CD8R T-cell responses prior to HIV acquisition
(2010)OBJECTIVE: Vaccine-induced CD8(+) T-cell responses in primates have been associated with a reduced simian immunodeficiency virus plasma viral load and enhanced T-cell responses, but cellular vaccines have shown limited ... -
CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa
(2009)Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African participants. ... -
Pregnancy rates among female participants in phase I and phase IIA AIDS vaccine clinical trials in Kenya
(2009)Female participants in AIDS candidate vaccine clinical trials must agree to use effective contraception to be enrolled into the studies, and for a specified period after vaccination, since the candidate vaccines’ effects ... -
Safety and immunogenicity of recombinant low-dosage HIV-1 A vaccine candidates vectored by plasmid pTHr DNA or modified vaccinia virus Ankara (MVA) in humans in East Africa
(2008)Summary: The safety and immunogenicity of plasmid pTHr DNA, modified vaccinia virus Ankara (MVA) human immunodeficiency virus type 1 (HIV-1) vaccine candidates were evaluated in four Phase I clinical trials in Kenya and ... -
Bacterial vaginosis in HIV-infected women induces reversible alterations in the cervical immune environment
(2008)Bacterial vaginosis (BV) has been associated with increased HIV cervicovaginal shedding. We hypothesized that this might relate to BV-associated increases in mucosal activated CD4+ T cells, which could enhance local HIV ... -
Negative mucosal synergy between Herpes simplex type 2 and HIV in the female genital tract
(2007)There is substantial epidemiological evidence that infection by Herpes simplex virus type 2 (HSV2) enhances both HIV susceptibility and subsequent sexual transmission. Both infections are extremely common in female sex ... -
Improving adherence to ante-retroviral treatment for people with harmful alcohol use in Kariobangi, Kenya through participatory research and action.
(2012-08)BACKGROUND: Harmful alcohol use has been linked to the spread of HIV in Kenya. It also adversely affects those on antiretroviral (ARV) treatment through poor compliance. This study using participatory research and action ... -
How Kenyan physicians treat psychiatric disorders.
(Department of Psychiatry, College of Health Sciences, University of Nairobi, 2001-04)OBJECTIVES: To determine the psychological problems the non-psychiatric doctors commonly encounter, the treatment offered and/or referrals made and to determine any obstacles met in providing psychiatric treatment or ... -
Psychiatric morbidity among leprosy patients in Teso and Busia districts of Western Kenya.
(2005-09)OBJECTIVE: To establish the magnitude of psychiatric disorders among leprosy patients in western Kenya. DESIGN: A cross-sectional descriptive study. SETTING: Busia and Teso districts in western Kenya. SUBJECTS: A ... -
What impact would an HIV/AIDS vaccine have on the HIV/AIDS epidemic in Kenya?
(2012-09)Objective: To estimate the potential impact of an HIV/AIDS Vaccine in Kenya. Design: The Kenyan HIV/AIDS epidemic was modeled using the most current data from national sources including epidemiology and behavioral surveillance. ... -
Psychiatric morbidity among convicted male sex offenders at Kamiti Prison, Kenya.
(Department of Psychiatry, School of Medicine, College of Health Sciences, University of Nairobi, 2007-04)OBJECTIVES: To determine the prevalence and distribution of psychiatric morbidity among convicted male sex offenders and to establish factors associated with sexual offending. DESIGN: A Cross-sectional descriptive ... -
Treatment with Antiretroviral Therapy is Not Associated with Increased Sexual Risk Behaviour in Kenyan Female Sex Workers
(2010-03)OBJECTIVE: The objective of this study was to test the hypothesis that sexual risk behavior would increase following initiation of antiretroviral therapy (ART) in Kenyan female sex workers (FSWs). DESIGN: Prospective ... -
Review Article on Africa Eye Programme : Kenya
(Department of Ophthalmology, School of Medicine, College of Health Sciences, University Of Nairobi, 2000) -
Sensitivity and specificity of HIV rapid tests used for research and voluntary counselling and testing
(2008-10)Background: HIV rapid tests (RT) are a quick and non-technically demanding means to perform HIV voluntary counselling and testing (VCT) but understanding their limitations is vital to delivering quality VCT. Objective: ... -
KAP of traditional healers on treatment of eye diseases in Kitui district of Kenya
(Department of Ophthalmology, School of Medicine, College of Health Sciences, University Of Nairobi, 2007)Objective: To establish the prevailing eye practices among traditional healers in Kitui district and establish whether these healers are able to identify ocular emergencies and refer in good time. Design: Community based ... -
Post traumatic stress disorder among motor vehicle accident survivors attending the orthopaedic and trauma clinic at Kenyatta National Hospital, Nairobi
(2004-07)OBJECTIVES: To determine the prevalence rate of post traumatic stress disorder (PTSD) and associated risk factors among motor vehicle accident (MVA) survivors attending the orthopaedic and trauma clinic at Kenyatta National ... -
Studies of a prophylactic HIV-1 vaccine candidate based on modified vaccinia virus Ankara (MVA) with and without DNA priming: Effects of dosage and route on safety and immunogenicity
(2006-11)Background: Two parallel studies evaluated safety and immunogenicity of a prophylactic HIV-1 vaccine in 192 HIV-seronegative, low-risk volunteers. Modified vaccinia virus Ankara (MVA) and plasmid DNA (pTHr) expressed HIV-1 ...
