Faculty of Health Sciences (FHS): Recent submissions
Now showing items 1521-1540 of 10417
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Outcome of the first medicines utilization research in Africa group meeting to promote sustainable and rational medicine use in Africa.
(University of Nairobi, 2015)The second Medicines Utilization Research in Africa (MURIA) group workshop and symposium again brought researchers together from across Africa to improve their knowledge of drug utilization (DU) methodologies and exchange ... -
Barriers to the uptake of postexposure prophylaxis among Nairobi-based female sex workers
(University of Nairobi, 2015-09)INTRODUCTION: Female sex workers (FSWs) in sub-Saharan Africa are at a particularly high risk for HIV infection. Postexposure prophylaxis (PEP) is available as part of an HIV care and prevention program through dedicated ... -
Anti-Retroviral Therapy Related Liver Injury A Series of 11 Cases
(University of Nairobi, 2014)Background: HIV Anti-retroviral therapy (ART) related liver injury (ARLI) is associated with elevated liver transaminases (AST/ALT), potential liver failure and death. It is commonly associated with nevirapine. Identification ... -
Reasons for Change of Anti-Retroviral Therapy (ART) Drugs: Local Experience
(University of Nairobi, 2014)Background: Highly active anti-retroviral therapy (HAART) reduces morbidity and mortality in HIV/AIDS infected patients. HAART is used indefinitely and the regimens are changed over the course of treatment due to resistance, ... -
Morbidity and CD4+ Cell Counts at Initial Presentation of a Cohort of HAART-Naive, HIV Positive Kenyan Patients: Implications to Initiating HAART
(University of Nairobi, 2014)Background: Sub-Saharan Africa with under 10% of the worldfs total population accounts for 60-70% of all HIV/AIDS cases. While these patients require HAART to manage the disease, HAART is not universally available. Majority ... -
CD4+ Cell Response to Anti-Retroviral Therapy (ARTS) In Routine Clinical Care Over One Oear Oeriod in a Cohort of HAART Naive, HIV Positive Kenyan Patients
(University of Nairobi, 2014)Background: Untreated HIV/AIDS leads to severe immune depletion with opportunistic infections and other co-morbidities. Highly active anti-retroviral ... -
Diabetes Mellitus/HIV Interphase: A Series of 10 Cases
(University of Nairobi, 2014)Background: Evidence shows that the use of protease inhibitors (PIs) in HIV/AIDS patients leads to the development of diabetes mellitus. Some degree of insulin resistance has also been noted in HIV infected patients not ... -
Cholangiopathy in a Co-Hort of HIV Positive Kenyan Patients
(University of Nairobi, 2014)Background: AIDS (acquired immunodeficiency syndrome) related cholangiopathy results from the inflammation of biliary tree and gall bladder. It is an uncommon manifestation of advanced HIV/AIDS that was associated with ... -
Pyomyositis in HIV: A Series of 12 Cases
(University of Nairobi, 2014)Background: Pyomyositis is a bacterial infection of the large skeletal muscles presenting with muscle pain and swelling. It is commonly seen in the tropics but is being recognised more in end-stage HIV/AIDS. In HIV-associated ... -
Use of mobile learning technology among final year medical students in Kenya
(University of Nairobi, 2015)Introduction Mobile phone penetration has increased exponentially over the last decade as has its application in nearly all spheres of life including health and medical education. This study aimed at assessing the use of ... -
Effect of daily antenatal iron supplementation on plasmodium infection in Kenyan women a randomized clinical trial
(University of Nairobi, 2015)Importance Anemia affects most pregnant African women and is predominantly due to iron deficiency, but antenatal iron supplementation has uncertain health benefits and can increase the malaria burden. Objective To ... -
Host Genetic and Viral Determinants of HIV-1 RNA Set Point among HIV-1 Seroconverters from Sub-Saharan Africa
(University of Nairobi, 2015-09-03)ABSTRACT We quantified the collective impact of source partner HIV-1 RNA levels, human leukocyte antigen (HLA) alleles, and innate re- sponses through Toll-like receptor (TLR) alleles on the HIV-1 set point. Data came ... -
Molecular signatures of immune activation and epithelial barrier remodeling are enhanced during the luteal phase of the menstrual cycle: implications for HIV susceptibility
(University of Nairobi, 2015)Variable infectivity and transmissibility of HIV/SHIV has been recently associated with the menstrual cycle, with particular susceptibility observed during the luteal phase in non-human primate models and ex vivo human ... -
Wheeze as an adverse event in pediatric vaccine and drug randomized controlled trials: A systematic review.
(University of Nairobi, 2015-08-25)INTRODUCTION: Wheeze is an important sign indicating a potentially severe adverse event in vaccine and drug trials, particularly in children. However, there are currently no consensus definitions of wheeze or associated ... -
The role of regulatory T cells in chronic and acute viral infections
(University of Nairobi, 2008)Regulatory T cells, a subset of CD4+ T lymphocytes, play a pivotal role in the maintenance of the balance between the tissue-damaging and protective effects of the immune response. These cells have immunosuppressive function ... -
A new pterocarpan from the leaves of Abrus precatorius L..
(University of Nairobi, 2015-07-17)A pterocarpan, 2,3,4,8-tetramethoxy-6a,11a-dihydro-6H-benzo[4,5]furo[3,2-c]chromene-7,9-diol (compound 1) was isolated from the dichloromethane extract of the leaves of Abrus precatorius L. The structure of the compound ... -
Mobile phone text messages for improving adherence to antiretroviral therapy (ART): a protocol for an individual patient data meta-analysis of randomised trials
(University of Nairobi, 2013)Introduction Mobile phone text messaging is emerging as an important tool in the care of people living with HIV; however, reports diverge on its efficacy in improving adherence to antiretroviral therapy (ART), and little ... -
Progress in policy issues to improve oral health in Africa
(University of Nairobi, 2004) -
Trichomonas vaginalis infection: can we afford to do nothing?
(University of Nairobi, 2008)For more than a century following its initial description in 1836, Trichomonas vaginalis was considered to be either a harmless vaginal colonizer or simply a minor nuisance [1]. This view may have been sustained by the ... -
Role of anthropology in young infant feeding
(University of Nairobi, 2015-08)Background : Infant feeding is crucial for growth and development of the child . It varies from one context to another including maternal HIV infection. Anthropologists examine infant ...
