Faculty of Health Sciences (FHS): Recent submissions
Now showing items 2741-2760 of 10418
-
Introgressive hybridization of human and rodent schistosome parasites in western Kenya.
(University of NairobiSchool of Medicine, 2008)Hybridization and introgression can have important consequences for the evolution, ecology and epidemiology of pathogenic organisms. We examined the dynamics of hybridization between a trematode parasite of humans, Schistosoma ... -
Serpiginous Choroiditis with Atypical Presentation Treated with Intravenous Methyl Prednisolone
(University of Nairobi, 2013-10-11)Abstract Purpose: The purpose of this study is to report a case of atypical serpiginous choroiditis presenting with disc edema and exudative retinal detachment, treated successfully with intravenous methyl prednisolone. ... -
Outcomes of the mental health and development model in rural Kenya: a 2-year prospective cohort intervention study
(University of Nairobi,Department of Psychiatry and Mental Health, 2013-03)Background: The aim of this study was to evaluate outcomes for participants in BasicNeeds' Mental Health and Development programme in rural Kenya. Methods All new entrants to the programme in the Meru South and Nyeri North ... -
Sympathetic Ophthalmia in Pediatric Age Group: Clinical Features and Challenges in Management in a Tertiary Center in Southern India
(University of Nairobi, 2013-10-16)Abstract Purpose: To study the clinical features and visual outcome of sympathetic ophthalmia in pediatric patients attending a tertiary care center. Methods: Retrospective review of patients ≤16 years with sympathetic ... -
Association of human rotavirus infection and intestinal rotavirus-specific immunoglobulin A in children with diarrhoea.
(University of NairobiCollege of Health Science, 1995)The purpose of this study was to determine the role of intestinal specific rotavirus IgA antibody in protection against diarrhoea due to rotavirus infection. Stool from children aged below 5 years with diarrhoea who reported ... -
Isolation and biological characterization of non-B HIV type 1 from Kenya
(School of Medicine, University of Nairobi, 2012-07)The isolation and characterization of primary strains of human immunodeficiency virus (HIV) is a vital tool for assessing properties of viruses replicating in HIV-infected subjects. HIV-1 isolation was carried out from 30 ... -
Evidence review of hydroxyurea for the prevention of sickle cell complications in low-income countries.
(school of public health, 2013-11)Hydroxyurea is widely used in high-income countries for the management of sickle cell disease (SCD) in children. In Kenyan clinical guidelines, hydroxyurea is only recommended for adults with SCD. Yet many deaths from SCD ... -
The epidemiology of Chlamydia trachomatis within a sexually transmitted diseases core group.
(University of NairobiCollege of Health Science, 1996)Female sex workers in Nairobi were prospectively evaluated for risk factors of incident Chlamydia trachomatis infection. Independent risk factors included cervical ectopy (P=.007), gonococcal infection (P=.002), human ... -
Schistosoma kisumuensis n. sp. (Digenea: Schistosomatidae) from murid rodents in the Lake Victoria Basin, Kenya and its phylogenetic position within the S. haematobium species group.
(University of NairobiSchool of Medicine, 2009)Schistosoma kisumuensis n. sp. is described based on 6 adult males and 2 adult females collected from the circulatory system of 3 murid rodent species, Pelomys isseli, Mastomys natalensis, and Dasymys incomtus. Specimens ... -
HLA-DR 52- and 51-associated DRB1 alleles in Kenya, east Africa.
(University of NairobiCollege of Health Science, 1997)Abstract The genes of the major histocompatibility complex (MHC) are amongst the most polymorphic loci known in the human population. The population genetics of the MHC encoded HLA loci of sub-Saharan Africa are of major ... -
Schistosomes of small mammals from the Lake Victoria Basin, Kenya: new species, familiar species, and implications for schistosomiasis control.
(University of NairobiSchool of Medicine, 2010)Recent schistosomiasis control efforts in sub-Saharan Africa have focused nearly exclusively on treatment of humans with praziquantel. However, the extent to which wild mammals act as reservoirs for Schistosoma mansoni and ... -
Antibody to chlamydial hsp60 predicts an increased risk for chlamydial pelvic inflammatory disease.
(University of NairobiCollege of Health Science, 1997)Abstract To determine whether serum antibody to Chlamydia trachomatis antigens alters the risk of C. trachomatis pelvic inflammatory disease (PID), 280 female sex workers were prospectively evaluated over a 33-month ... -
Recent transmission of tuberculosis in a cohort of HIV-1-infected female sex workers in Nairobi, Kenya.
(University of Nairobic, 1997)Abstract OBJECTIVES: To describe the epidemiological and clinical characteristics of HIV-related tuberculosis in a female cohort, and to investigate the relative importance of recently transmitted infection and ... -
Geographical variation in the response of visceral leishmaniasis to paromomycin in East Africa: a multicentre, open-label, randomized trial.
(University of NairobiSchool of Medicine, 2010)BACKGROUND: Visceral leishmaniasis (VL) is a major health problem in developing countries. The untreated disease is fatal, available treatment is expensive and often toxic, and drug resistance is increasing. Improved ... -
Misdiagnosed adult testicular torsion: case report.
(University of NairobiCollege of Health Science, 2009)Adult testicular torsion is thought to be rare if not relatively unusual. The rarity could be an underestimation since there are many episodes of missed torsions and misdiagnosis with other conditions of acute scrotum ... -
Pharmacokinetics and clinical efficacy of lorazepam in children with severe malaria and convulsions.
(University of NairobiDepartment of Pharmaceutics and Pharmacy Practice, Faculty of Pharmacy, University of Nairobi, 2008-01)AIM: To investigate the pharmacokinetics and clinical efficacy of intravenous (i.v.) and intramuscular (i.m.) lorazepam (LZP) in children with severe malaria and convulsions. METHODS: Twenty-six children with severe ... -
Risk factors for kerosene stove explosion burns seen at Kenyatta National Hospital in Kenya.
(University of NairobiCollege of Health Science, 2012)BACKGROUND: The kerosene stove is a common cooking appliance in lower and middle income households in Kenya and if it explodes, life threatening thermal burn injuries may be sustained by those using the appliance. Women ... -
Interactions between natural populations of human and rodent schistosomes in the Lake Victoria region of Kenya: a molecular epidemiological approach.
(University of NairobiSchool of Medicine, 2008)BACKGROUND: Schistosoma mansoni exists in a complex environmental milieu that may select for significant evolutionary changes in this species. In Kenya, the sympatric distribution of S. mansoni with S. rodhaini potentially ... -
Chronic bilateral heel pain in a child with Sever disease: case report and review of literature.
(University of Nairobi,Department of Orthopaedic surgery, 2009-12)We are presenting a case report of a 10-year-old male with a 1 year history of bilateral heel pain. Sever disease is self limiting condition of calcaneal apophysis. It is the most common cause of heel pain in the growing ... -
Spontaneous Vitreous Hemorrhage in Children
(University of Nairobi, 2013-08-06)PURPOSE: To determine the clinical profile, causes, and outcomes of "spontaneous" vitreous hemorrhage in children (<18 years). DESIGN: Retrospective computer-assisted chart review. METHODS: Charts of 124 eyes ...
