Faculty of Health Sciences (FHS): Recent submissions
Now showing items 4641-4660 of 10418
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The Levels of CD16/Fcγ Receptor IIIA on CD14+ CD16+ Monocytes Are Higher in Children with Severe Plasmodium falciparum Anemia than in Children with Cerebral or Uncomplicated Malaria
(Department of Biochemistry, 2010-05)Fc gamma receptor IIIA (CD16/FcγRIIIA) on monocytes/macrophages may play an important role in the pathogenesis of severe malarial anemia (SMA) by promoting phagocytosis of IgG-coated uninfected red cells and by allowing ... -
Elevation Of Immune Activation In Kenyan Women Is Associated With Alterations In Immune Function: Implications For Vaccine Development.
(University of NairobiDepartment of Medical Microbiology, 2004-11)The infectious burden leading to immune activation can vary between different populations and lead to various immune dysfunctions. We compared the effect of immune activation on apoptosis and T cell function in HIV uninfected ... -
Lack of Fetuin-A (α2-HS-Glycoprotein) Reduces Mammary Tumor Incidence and Prolongs Tumor Latency via the Transforming Growth Factor-β Signaling Pathway in a Mouse Model of Breast Cancer
(Department of Biochemistry, 2010-11)The present analyses were done to define the role of fetuin-A (Fet) in mammary tumorigenesis using the polyoma middle T antigen (PyMT) transgenic mouse model. We crossed Fet-null mice in the C57BL/6 background with PyMT ... -
Vaccination of the vervet monkey (Cercopithecus aethiops) against infection with Schistosoma mansoni.
(Department of Human Pathology,University of Nairobi, 1992)Pilot experiments were carried out to assess the immunizing potential of radiation-attenuated cercariae of S. mansoni. Groups of 4 monkeys each were vaccinated 4-5 times at 3-5-week intervals using cercariae which had ... -
Increased deposition of C3b on red cells with low CR1 and CD55 in a malaria-endemic region of western Kenya: Implications for the development of severe anemia
(Department of Biochemistry, 2008)Severe anemia due to Plasmodium falciparum malaria is a major cause of mortality among young children in western Kenya. The factors that lead to the age-specific incidence of this anemia are unknown. Previous studies have ... -
Polymorphisms In Irf-1 Associated With Resistance To Hiv-1 Infection In Highly Exposed Uninfected Kenyan Sex Workers
(University of NairobiDepartment of Medical Microbiology, 2007-05)OBJECTIVE: To determine the correlation between polymorphisms in the IL-4 gene cluster and resistance to HIV-1 infection. DESIGN: : A cross-sectional genetic analysis of polymorphisms within the IL-4 gene cluster ... -
Human Interferon Regulatory Factor-1 Gene And Its Promoter Sequences Revealed By Population-based Complete Gene Sequencing.
(University of NairobiDepartment of Medical Microbiology, 2008-06)Interferon regulatory factor-1 (IRF-1) plays important roles in host immunity, cell proliferation and apoptosis. The current GenBank sequence for human IRF-1 (accession number: L05072) was derived from a human placenta DNA ... -
A Short Communication-Isolation and characterization of Bacillus thuringiensis from coastal intertidal brackish sediments and from farmlands in Machakos District Kenya
(University of Nairobi,College of Health Sciences,, 2012)Bacillus thuringiensis (Bt) delta endotoxins represent the most successful use of biological control agents targeting crop pests to date. Studies have shown that Bt produces a wider range of toxins targeting ... -
The development of schistosomiasis mansoni in an immunologically naive immigrant population in Masongaleni, Kenya.
(University of Nairobi,, 1998-08)The relocation of several thousand members of the Kamba tribe from the Kyulu Hills to the Thange valley near Masongaleni in Kenya provides an excellent opportunity to study the development of the immune response to ... -
An Integrative Bioinformatic Approach For Studying Escape Mutations In Human Immunodeficiency Virus Type 1 Gag In The Pumwani Sex Worker Cohort.
(University of NairobiDepartment of Medical Microbiology, 2008-02)Human immunodeficiency virus type 1 (HIV-1) is able to evade the host cytotoxic T-lymphocyte (CTL) response through a variety of escape avenues. Epitopes that are presented to CTLs are first processed in the presenting ... -
Immunogenic proteins in the body and faecal material of the human body louse, Pediculus humanus, and their homology to antigens of other lice species
(College of Health Sciences,, 2008-06) -
Attempted infection of calves with Taenia crocutae cysticerci and their subsequent serological response.
(University of Nairobi,, 1985-05)The susceptibility of naive cattle to infection with cysticerci of Taenia crocutae was tested using three six- to nine-month-old Ayrshire bull calves, previously unexposed to infection with taeniid eggs. One calf was given ... -
Invasive pneumococcal disease in a cohort of predominantly HIV-1 infected female sex-workers in Nairobi, Kenya
(Department of Medical Microbiology, University of Nairobi , United KingdomClinical Research Centre, Kenya Medical Research Institute, Nairobi, KenyaCentre for Microbiology Research, Kenya Medical Research Institute, Nairobi, KenyaUniversity of Winnipeg, Manitoba, CanadaCentre for Tropical Medicine, University of Oxford, Oxford, UK, 1996-03)Background HIV infection is a major risk factor for pneumococcal disease in industrialised countries. Although both are common infections in sub-Saharan Africa, few studies have investigated the importance of this interaction. ... -
aenia saginata infection in East African antelopes.
(University of Nairobi,Department of Pharmacology and Toxicology, 1982-10)No abstract -
Full-length Hiv Type 1 Proviral Sequencing Of 10 Highly Exposed Women From Nairobi, Kenya Reveals A High Proportion Of Intersubtype Recombinants.
(University of NairobiDepartment of Medical Microbiology, 2008-06)Phylogenetic analysis has revealed that the current HIV/AIDS pandemic consists of a multitude of different viral clades and recombinant viruses. The predominant circulating HIV-1 clade in Kenya is A1; however, Kenya borders ... -
Decreased Immune Activation In Resistance To Hiv-1 Infection Is Associated With An Elevated Frequency Of Cd4(+)cd25(+)foxp3(+) Regulatory T Cells.
(University of NairobiDepartment of Medical Microbiology, 2009-05)Human immunodeficiency virus (HIV)-resistant commercial sex workers provide a unique opportunity to study correlates of protection associated with natural resistance to HIV infection. Emerging data from studies of these ... -
Ovarian cancer in Kenyatta National Hospital in Kenya: Characteristics and management
(University of Nairobi,Department of Obstetrics & Gynaecology,, 2013) -
Same day colposcopic examination and loop electrosurgical excision procedure (LEEP) presents minimal overtreatment and averts delay in treatment of cervical intraepithelial neoplasia in Kenyatta National Hospital, Kenya
(University of Nairobi,Department of Obstetrics & Gynaecology,, 2013) -
Robbed of Choice: Forced and Coerced Sterilization experiences of Women living with HIV in Kenya by African Gender and Media Initiative
(University of Nairobi,Department of Obstetrics & Gynaecology,, 2012) -
Editorial Female genital mutilation situation analysis in Africa
(University of Nairobi,Department of Obstetrics & Gynaecology,, 2011)
