Faculty of Health Sciences (FHS): Recent submissions
Now showing items 8721-8740 of 10418
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Clinical epidemiology in patients admitted at Mathari Psychiatric Hospital, Nairobi, Kenya.
(Africa Mental Health Foundation, Nairobi, KenyaDepartment of Psychiatry, University of Nairobi, Nairobi, Kenya;, 2008-09)Background: Knowledge of types and co-morbidities of disorders seen in any facility is useful for clinical practice and planning for services. Aim: To study the pattern of co-morbidities of and correlations between ... -
Effect of renal insufficiency on the pharmacokinetics of cyclophosphamide and some of its metabolites
(1981)Cyclophosphamide pharmacokinetics were studied in seven patients with moderate to severe renal insufficiency (creatinine clearances 0-51 ml . min-1), and compared with a matched control group of patients with normal renal ... -
Adherence to oral rehydration therapy among in-patient children aged 1-59 months with some or no dehydration
(Department of paediatrics, University of Nairobi, 2009-07)OBJECTIVE: To determine adherence to oral rehydration solution (ORS) among in-patients aged 1-59 months suffering from gastroenteritis and having some dehydration (SD) or no dehydration (ND) in two rural hospitals in ... -
Cutaneous basal cell carcinoma in Kenya.
(Department of Medicine, University of Nairobi., 1999)Primary basal cell carcinoma(BCC) of the skin is the commonest tumour in Caucasians. Its incidence and mode of presentation in Kenyan Africans are unknown. To study the incidence and mode of presentation of BCC in ... -
The kinetics of salivary elimination of cyclophosphamide in man.
(1979)The concentrations of cyclophosphamide in plasma and saliva were determined in seven patients following administration of single doses of cyclophosphamide during chemotherapy for lymphoma. 2 The saliva/plasma ratio was ... -
Exfoliative erythroderma at Kenyatta National Hospital, Nairobi.
(Department of Clinical Medicine and Therapeutics, College of Health Sciences, University of Nairobi, 2007)Exfoliative erythroderma (EE), (Synonyms: Exfoliative dermatitis, Red man syndrome) is a clinical syndrome characterised by generalised erythema and scale. It is an important cause of functional skin failure and associated ... -
Measuring drug prices in low and middle income countries. The Kenya Report:
(Medicine, University of Nairobi, 2001)No Abstract -
Pharmacokinetics of cyclophosphamide and alkylating activity in man after intravenous and oral administration.
(1979)Since cyclophosphamide is used by both oral and i.v. routes in the treatment of hematological and solid malignancies, we designed a randomized, crossover clinical trial to evaluate the pharmacokinetics of this anticancer ... -
Health information in the developing world
(2001-07)OBJECTIVE: To assess the clinical outcome of successful percutaneous transluminal coronary angioplasty (PTCA) in patients with poor ventricular function. METHODS: Analysis of angiographic, echocardiographic and clinical ... -
First pass hepatic metabolism of cyclophosphamide [proceedings].
(1979)Cyclophosphamide itself has no alkylating activity and does not posses cytostatic effect in vitro. In vivo it undergoes activation initially by hepatic micr-somal mixed function oxidase to a number of alkylating metabolites ... -
. Development and validation of a liquid chromatographic method for the simultaneous analysis of anticonvulsant drugs
(Medicine, University of Nairobi, 2002)No Abstract -
Directed evolution of the alpha-L-fucosidase from Thermotoga maritima into an alpha-L-transfucosidase.
(2007)The alpha-L-fucosidase from Thermotoga maritima (Tm alpha fuc) was converted into alpha-L-transfucosidase variants by directed evolution. The wild-type enzyme catalyzes oligosaccharide synthesis by transfer of a fucosyl ... -
Directed evolution of the alpha-L-fucosidase from Thermotoga maritima into an alpha-L-transfucosidase
(Department of Medicine. College of Health Sciences. University of Nairobi, 2007)The alpha-L-fucosidase from Thermotoga maritima (Tm alpha fuc) was converted into alpha-L-transfucosidase variants by directed evolution. The wild-type enzyme catalyzes oligosaccharide synthesis by transfer of a fucosyl ... -
Impact of counselling on exclusive breast-feeding practices in a poor urban setting in Kenya: a randomized controlled trial.
(Department of paediatrics, University of Nairobi, 2012-10)OBJECTIVE: To determine the impact of facility-based semi-intensive and home-based intensive counselling in improving exclusive breast-feeding (EBF) in a low-resource urban setting in Kenya. DESIGN: A cluster ... -
Predicting the outcome of revascularization in ischaemic left ventricular dysfunction
(Department of Medical Physiology, College of Health Sciences, University of Nairobi, 2000-08)OBJECTIVE: To assess the clinical outcome of successful percutaneous transluminal coronary angioplasty (PTCA) in patients with poor ventricular function. METHODS: Analysis of angiographic, echocardiographic and clinical ... -
Pharmacokinetics of intravenous cyclophosphamide in man, estimated by gas-liquid chromatography.
(1978)A simple gas chromatographic assay utilising alkali flame ionisation detection is described for the estimation of cyclophosphamide as its trifluoroacetate derivative from plasma. Examination of five patients following ... -
Psychiatric morbidity among sexually abused children and adolescents.
(Mathari Hospital, Nairobi, KenyaDepartment of Psychiatry, University of Nairobi, Nairobi, Kenya;, 2008-02)OBJECTIVES: To describe the social demographic profile and identify psychiatric morbidity in sexually abused children and adolescents. DESIGN: A Cross-sectional descriptive survey. SETTING: Nairobi Women's Hospital ... -
Haemoglobin A1C in children with sickle cell disease.
(1984)Despite the high frequency of sickle cell disease in Europe, the disease is poorly managed. Critical periods are the hospital stays during which the anaesthesiologist plays an important role. Understanding the molecular ... -
Liquid chromatographic analysis of phenobarbitone, ethosuximide, phenytoin and carbamazepine on a polystyrene-divinyl benzene column
(Medicine, University of Nairobi, 2006)A liquid chromatographic method for the simultaneous assay of four anticonvulsant drugs, phenobarbitone, ethosuximide, phenytoin and carbamazepine on a polystyrene-divinyl benzene column is described. The method was developed ... -
Neutralizing antibody escape during HIV-1 mother-to-child transmission involves conformational masking of distal epitopes in envelope.
(Department of paediatrics, University of Nairobi, 2012-09)HIV-1 variants transmitted to infants are often resistant to maternal neutralizing antibodies (NAbs), suggesting that they have escaped maternal NAb pressure. To define the molecular basis of NAb escape that contributes ...
