Faculty of Health Sciences (FHS): Recent submissions
Now showing items 9281-9300 of 10418
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Antibody and T-cell responses during acute and convalescent stages of invasive pneumococcal disease.
(Department of Medicine. College of Health Sciences. University of Nairobi, 2011-04)OBJECTIVE: To understand the pattern of immune responses to pneumococcal proteins during invasive disease as a guide to their development as vaccine candidates. METHODS: The antibody concentration and avidity, as well ... -
Changing pattern of intracranial lesions
(2000)Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing ... -
Neurological manifestations following partial excision in spinal meningioma: case report
(2007)Presented here is a 16-year-old girl who was referred on 30th January 1996 with diagnosis of cord compression with spastic paraplegia with sensory level at T7/T8. CT scan myelogam confirmed soft tissue density mass displacing ... -
Improvement of vaginal health for Kenyan women at risk for acquisition of human immunodeficiency virus type 1: results of a randomized trial
(Department of Medicine, University of Washington, Seattle, USADepartment of Medical Microbiology, NairobiDepartment of Obstetrics and Gynecology, University of Nairobi, NairobiDepartment of Coast Provincial General Hospital, Mombasa, KenyaDepartment of Medicine, Seattle, 2008)BACKGROUND: Vaginal infections are common and have been associated with increased risk for acquisition of human immunodeficiency virus type 1 (HIV-1). METHODS: We conducted a randomized trial of directly observed oral ... -
Preservation HIV-1-specific IFNγ+ CD4+ T-cell responses in breakthrough infections after exposure to tenofovir gel in the CAPRISA 004 microbicide trial.
(Department of Medicine. College of Health Sciences. University of Nairobi, 2012-06)The Centre for the AIDS Program of Research in South Africa 004 trial demonstrated reduction of sexual HIV-1 acquisition in women using a vaginal microbicide containing tenofovir. A better understanding of the consequences ... -
A prospective study of risk factors for bacterial vaginosis in HIV-1-seronegative African women
(Department of Medicine, University of Washington, Seattle, WA 98104, USA, 2008)Bacterial vaginosis (BV) is common and has been associated with increased HIV-1 susceptibility. The objective of this study was to identify risk factors for BV in African women at high risk for acquiring HIV-1. We conducted ... -
Obstetric Fistula: An Avoidable Outcome of the Three Classic Delays
(2006)Antibody responses to a conventional rabies preexposure regimen of a new purified Vero cell rabies vaccine (PVRV) and a human diploid cell vaccine (HDCV) were compared in 80 healthy Kenyan veterinary students. Forty-three ... -
Lymphatic pumping in response to changes in transmural pressure is modulated by erythrolysate/hemoglobin
(1990)Red blood cells and lysate products (erythrolysate) are observed consistently in lymph draining acute and chronic inflammatory reactions and from tissues subjected to trauma or surgical procedures. Using hemoglobin as a ... -
Haeme-containing proteins suppress Lymphatic Pumping
(1992)Red blood cells (RBCs) and lysate products (erythrolysate) are consistently observed in lymph draining inflammatory reactions and from tissues subjected to trauma or surgical procedures. We determined previously that ... -
Use of Restriction Fragment Length Polymorphism of 18S rRNA Gene for Identification of Trypanosome and Other Protozoan Species
(The Kenya Veterinarian, 2005)Oligonucleotide primers based on conserved nucleotide sequences of 18S ribosomal RNA (18S rRNA) gene of Trypanosoma brucei, Leishmania donovani, Triponema aequale and Legenidium gigantum were designed, synthesized and used ... -
Trypanosoma (nannomonas) congolense
(The Kenya Veterinarian, 2004)Pulsed field gradient gel electrophoresis was used to separate chromosomes of parasitic protozoan Trypanosome congolense clone IL1180. Total trypanosome DNA was isolated and resolved into 18 chromosomes by pulsed-field ... -
RAPD analysis of genotypic groups of Trypanosoma congolense and other African trypanosome species
(2006)Oligonucleotide primers of arbitrary nucleotide sequences were used in PCR reaction to amplify genomic DNA from the four types of T. congolense: Tsavo-type, Savannah-type, Kilifi-type and West African riverine/ forest-type. ... -
Predicted HIV-1 coreceptor usage among Kenya patients shows a high tendency for subtype d to be cxcr4 tropic
(2012)Background: CCR5 antagonists have clinically been approved for prevention or treatment of HIV/AIDS. Countries in Sub-Saharan Africa with the highest burden of HIV/AIDS are due to adopt these regimens. However, HIV-1 can ... -
Dermatophyte infections in primary school children in Kibera slums of Nairobi
(Department of Medical Microbiology, University of NairobiSchool of Nursing, 2009)OBJECTIVE: To determine the prevalence and aetiology of dermatophyte infections in relation to social economic factors in primary school children in Kibera. DESIGN: A cross-sectional descriptive study. SETTING: City ... -
Plasmid Borne Resistance in Klebsiella Isolates from Kenyatta National Hospital, Nairobi, Kenya
(Department of Pharmaceutics & Pharmacy Practice, University of NairobiDepartment of Biochemistry, University of Nairobi, 2008)Eighty six Klebsiella isolates from Kenyatta National Hospital and the Centre for Microbiology, Kenya Medical Research Institute, Nairobi were screened for resistance to commonly prescribed antimicrobial agents and for ... -
Emergence of new types of Theileria orientalis in Australian cattle and possible cause of theileriosis outbreaks
(2011)Theileria parasites cause a benign infection of cattle in parts of Australia where they are endemic, but have, in recent years, been suspected of being responsible for a number of outbreaks of disease in cattle near the ... -
A specific enzyme-linked immunosorbent assay (ELISA) procedure for detection of heterophile Hanganutziu and Deicher (HD) antibodies
(College of Health Sciences, University of Nairobi, 1986-02-12)A specific, relatively sensitive, quantitative and standardized enzyme-linked immunosorbent assay (ELISA) procedure was developed for the detection of heterophile Hanganutziu and Deicher (HD) antibodies which are occasionally ... -
Carbohydrate active enzymes (Cazymes) as drug targets and tools for synthesis of medicinal compounds
(Department of Medicine. College of Health Sciences. University of Nairobi, 2011)No abstract -
Elevation of Heterophilic antibodies to rabbit erythrocytes in human pathologic sera: quantitative studies by Elisa using a Glycosphingolipid antigen
(College of Health Sciences, University of Nairobi, 1987)Human heterophilic hemagglutinin to rabbit erythrocytes was quantitatively determined by the hemagglutination test and enzyme linked immunosorbent assay (ELISA) using rabbit erythrocyte pentaglycosyl ceramide (CPH), Gal ... -
Widow inheritance and HIV prevalence in Bondo District, Kenya: baseline results from a prospective cohort study
(Department of Research, Impact Research and Development Organization, Kisumu, KenyaDepartment of Epidemiology, School of Public Health, University of Washington, Seattle, Washington, United States of AmericaDepartment of Epidemiology, University of Michigan, Ann Arbor, Michigan, United States of AmericaCenter for Microbiology Research, Kenya Medical Research Institute, Nairobi, KenyaDepartment of Medical Microbiology, University of Nairobi, Nairobi, KenyaDepartment of Community Health Sciences and Medical Microbiology, University of Manitoba, Winnipeg, Canada, 2010)BACKGROUND: Widow Inheritance is a widespread cultural practice in sub-Saharan Africa that has been postulated as contributing to risk of HIV transmission. We present baseline results from a study designed to investigate ...
