Faculty of Health Sciences (FHS): Recent submissions
Now showing items 10381-10400 of 10418
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Ocular findings in children attending occupational therapy clinic at Kenyatta National Hospital, Nairobi, Kenya
(2009-07)Objectives: To describe the pattern of ocular abnormalities, their correlation with the physical disorders and describe associated risk factors in children attending the Occupational therapy clinic at Kenyatta National ... -
What is the appropriate age range of individuals to be included in a survey to estimate the prevalence of trachomatous trichia sis?
(Department of Community Health, University of Nairobi, 2011)Introduction A survey to determine the prevalence of trachomatous trichiasis (TT) requires a large sample size and the recommended participant age is$15 years. This study sought to establish the appropriate age range of ... -
Epitope Cross-Reactivity Frequently Differs between Central and Effector Memory HIV-Specific CD8 T Cells1
(2007)HIV diversity may limit the breadth of vaccine coverage due to epitope sequence differences between strains. Although amino acid substitutions within CD8 T cell HIV epitopes can result in complete or partial abrogation ... -
Alcohol dependence: Does the composition of the available beverages promote it?
(Department of Psychiatry, University of Nairobi, Nairobi, 2012-10)Affordability and availability of alcohol are factors that have been associated with alcohol dependence. Ethanol content in the alcoholic beverages is an im- portant determinant in alcohol dependence. Quality control ... -
Are Blind People More Likely to Accept Free cataract Surgery? A Study of Vision-related Quality of Life and Visual Acuity in Kenya
(Department of Ophthalmology, College of Health Sciences, School of Medicine, 2010)Purpose: To determine possible differences in visual acuity, socio-demographic factors and visionrelated Quality of Life (QoL) between people accepting and people refusing sponsored cataract surgery. Methods: Three hundred ... -
Developing standards of care for HIV prevention research in developing countries – a case study of ten research centers in Eastern and Southern Africa
(2012-09)Background: Standards of care in general vary across countries and communities and thus may affect decisions about standards of care provided by research centers in HIV prevention research. To serve as a basis for ... -
Risk factors, management and outcomes of adverse drug reactions in adult patients on antiretrovirals at Kenyatta national hospital, Nairobi
(2010-02)Background: Antiretrovirals have been associated with serious adverse drug reactions. Several factors have been suggested as independent risk factors for their development. Identification of these factors may help in ... -
CLSI-Derived Hematology and Biochemistry Reference Intervals for Healthy Adults in Eastern and Southern Africa
(2/6/2009)Background: Clinical laboratory reference intervals have not been established in many African countries, and non-local intervals are commonly used in clinical trials to screen and monitor adverse events (AEs) among African ... -
An Assessment of the extent of Rational use of Antibiotics in surgical prophylaxis at Kenyatta National Hospital, Kenya
(Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, Kenya, 2011) -
Prescription Audit carried out at the Pharmacy Practice Centre of the University of Nairobi between June and November 2004
(Department of Pharmaceutics and Pharmacy Practice, School of Pharmacy, University of Nairobi, 2007)A retrospective descriptive study was carried out from June to November 2004 in a retail pharmacy situated at the School of Pharmacy, University of Nairobi within the Kenyatta National Hospital complex. The objective ... -
Blunted IL17/IL22 and pro-inflammatory cytokine responses in the genital tract and blood of HIV Exposed, seronegative female sex workers in Kenya
(2012)Identifying the immune correlates of reduced susceptibility to HIV remains a key goal for the HIV vaccine field, and individuals who are HIV-exposed, seronegative (HESN) may offer important clues. Reduced systemic immune ... -
PREVALENCE OF ADVERSE DRUG REACTIONS IN ADULT PATIENTS ON ANTI-RETROVIRALS AT KENYATTA NATIONAL HOSPITAL, COMPREHENSIVE CARE CENTRE
(College of Health Sciences, University of Nairobi,, 2009-12)ABSTRACT Background: There has been an increased access to anti-retrovirals in resourceconstrained settings. However, few studies have addressed the area of adverse drug reactions in these settings. Objective: To ... -
Anal Sex, Vaginal Practices, and HIV Incidence in Female Sex Workers in Urban Kenya: Implications for the Development of Intravaginal HIV Prevention Methods
(2011)Multiple intravaginal HIV prevention methods, including microbicide gels, barriers, and intravaginal rings, are in clinical development in Africa. Development of intravaginal HIV prevention products requires an understanding of ... -
Establishing and sustaining a healthy vaginal environment:
(2011)Data from a randomized trial of oral periodic presumptive treatment (PPT) to reduce vaginal infections were analyzed to assess the effect of the intervention on a healthy vaginal environment (normal flora confirmed by ... -
Prospective study of correlates of vaginal Lactobacillus colonisation among high-risk HIV-1 seronegative women
(2011)OBJECTIVE: Vaginal colonisation with Lactobacillus species is characteristic of normal vaginal ecology. The absence of vaginal lactobacilli, particularly hydrogen peroxide (H(2)O(2))-producing isolates, has been associated ... -
AIDS Vaccines and Preexposure Prophylaxis: Is Synergy Possible?
(2011)While the long-term goal is to develop highly effective AIDS vaccines, first generation vaccines may be only partially effective. Other HIV prevention modalities such as preexposure prophylaxis with antiretrovirals ... -
Hormonal contraceptive use, herpes simplex virus infection, and risk of HIV-1 acquisition among Kenyan women
(2007)Studies of the effect of hormonal contraceptive use on the risk of HIV-1 acquisition have generated conflicting results. A recent study from Uganda and Zimbabwe found that women using hormonal contraception were at increased ... -
HIV-1 subtype D infection is associated with faster disease progression than subtype A in spite of similar plasma HIV-1 Loads
(2007)We investigated the effect of human immunodeficiency virus type 1 (HIV-1) subtype on disease progression among 145 Kenyan women followed from the time of HIV-1 acquisition. Compared with those infected with subtype A, ... -
Reasons for ineligibility in phase 1 and 2A HIV vaccine clinical trials at Kenya Aids vaccine initiative (KAVI), Kenya
(2011)With the persistent challenges towards controlling the HIV epidemic, there is an ongoing need for research into HIV vaccines and drugs. Sub-Saharan African countries--worst affected by the HIV pandemic--have participated ...
