Faculty of Health Sciences (FHS): Recent submissions

Now showing items 4701-4720 of 10418

    • Aflatoxicosis: health implications. 

      Mwanda, OW (University of NairobiCollege of Health Sciences,University of Nairobi, 2005)

    • Identification and characterization of HLA-A*0301 epitopes in HIV-1 gag proteins using a novel approach 

      Semeniuk, Christina A.; Capina, Rupert E.; Mendoza, Mark G.R.; Kimani, Joshua; Ball, T. Blake; Ma Luo; Plummer, Francis A. (Department of Medical Microbiology, University of Nairobi, Nairobi, KenyaNational Microbiology Laboratory, 1015 Arlington Street, Winnipeg, Manitoba, CanadaDepartment of Medical Microbiology, University of Manitoba, 730 William Avenue, Winnipeg, Manitoba, Canada, 2010-01)
      Identification of CTL epitopes correlated to immune protection is important for the development of vaccines that enhance T-cell mediated immune responses. The correlation of positively selected amino acids (PS) of HIV-1 ...

    • Kasabach merritt syndrome in an adult female African : case report 

      Mwanda, OW; Wanjohi, EW; Cheserem, EN (University of NairobiDepartment of obstetrics and gynaecology,University of Nairobi., 1990)
      A case of KMS in a 25 year old female African is described. Her past medical history, laboratory findings and management are presented. The findings in this case are found to be in common with those in published cases. ...

    • Lupus anticoagulant syndrome: case report. 

      Mwanda, OW (University of NairobiDepartment of Haematology and Blood Transfusion, College of Health Sciences, University of Nairobi., 1998)
      A twenty seven year old female was referred to our department with deep vein thrombosis, abnormal activated partial thromboplastin time (aPTT) ratio 1:60 and prothrombin time (PT) INR of 3:11. She had history of loss of ...

    • Haematological changes in human immunodeficiency virus infection. Part I: Review article 

      Mwanda, OW (University of NairobiCollege of Health Sciences,University of Nairobi, 1997)
      This review attempts to put together the changes in the blood and bone marrow observed in those who are infected with human immunodeficiency virus (HIV). These are contribution of many published and unpublished data and ...

    • New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers 

      Kaula, Rupert B.; Rowland-Jones, Sarah L.; Kimania, Joshua; Fowkec, Keith; Dong, Tao; Kiamaa, Peter; John Rutherfordc, John; Njagia, Ephantus; Mwangia, Francis; Rostron, Tim; Onyango, James; Oyugi, Juliaas; Macdonald, Kelly S.; Bwayo, Job J.; Plummer, Francis A.; Fowke, Keith (Department of Medical Microbiology, University of Nairobi, Nairobi, KenyaDepartment of Medical Microbiology, University of Manitoba, Winnipeg, Manitoba, CanadaMRC Human Immunology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Oxford OX3 9DS, UK, 2001)
      A clearer understanding of HIV-1 specific immune responses in highly-exposed, persistently seronegative (HEPS) subjects is important in developing models of HIV-1 protective immunity. HIV-1 specific cytotoxic T-lymphocytes ...

    • Feasibility of screening for pre-malignant lesions in an Africa Environment, in virus-associated cancers in Africa 

      Mati, JKG; Mbugua, S; Ndavi, PM (University of Nairobi,Department of Obstetrics & Gynaecology, 1984)

    • Relapse of Hodgkin's disease after 10 years of complete remission: Case report. 

      Othieno-Abinya, N; Mwanda, OW (University of NairobiDepartment of Clinical Medicine and Therapeutics, 1998-03)
      A 17 year old male patient with nodular sclerosis Hodgkin's disease had a relapse of lymphocyte depleted type ten years after entering complete remission with chemotherapy and radiotherapy. This is the first documented ...

    • Acute aflatoxicosis: Case report 

      Mwanda, OW; Otieno, CF; Omonge, E (University of NairobiCollege of Health Sciences,University of Nairobi, 2005)
      The objective of this presentation is to document the salient clinical findings in a case of aflatoxicosis and to review the literature on the same so as to increase the index of suspicion, enhance early diagnosis and ...

    • Symptom screening: diagnostic usefulness to detect pulmonary tuberculosis in HIVinfected pregnant women in Kenya 

      Kosgei, Rj; Ndavi, PM; O’ech Joajmsamw-kk, Fojo T; Mwangi, A Mremejchte. (University of Nairobi,Department of Obstetrics & Gynaecology, 2011)

    • Megaloblastic marrow in macrocytic anaemias at Kenyatta national and M P Shah Hospitals, Nairobi 

      Dave P.; Mwanda O Walter. (University of NairobiDepartment of Haematology and Blood Transfusion, College of Health Sciences, University of Nairobi, 1999)
      Objective: To determine the diagnostic value of megaloblastic marrow in patients with possible vitamin B12 and/or folate deficiency and to look for criteria that could be used in diagnosis of vitamin B12 deficiency. Design: ...

    • Cellular kinetic and phenotypic heterogeneity in and among Burkitt’s and Burkitt’s-like lymphomas 

      Cottier, H; Laissue, JA; Kraft, R; Pileri, S; Nyong'O, A; Abinya, O; Tosi, P; Disanto, A; Gallorini, M; Megha, T; Leoncini, L; Spina, D (Department of Clinical Medicine and Therapeutics, 1997-06)
      This study asks whether the known genotypic heterogeneity within and between endemic or sporadic Burkitt's lymphomas (eBLs and sBLs, n = 10 each), and Burkitt-like lymphomas (BLLs, n-12), is reflected in divergent cytokinetics ...

    • Kaposi's sarcoma in patients with and without human immunodeficiency virus infection, in a tertiary referral centre in Kenya 

      Mwanda, Walter O; Fu, P; Collea, R; Whalen, C; Remick, S C (University of NairobiDepartment of Haematology and Blood Transfusion, College of Health Sciences, University of Nairobi, 2005-01)
      The clinical features of Kaposi's sarcoma (KS), in patients with and without HIV infection, were investigated in a tertiary referral centre in Kenya between 1997 and 1999. Although 186 cases were identified prospectively, ...

    • Comparing walk-in and call-responsive donors in a national and a private hospital in Nairobi 

      Abdalla F.; Mwanda Walter O.; Rana F. (University of NairobiCollege of Health Sciences,University of Nairobi, 2005)
      Background: The non-remunerated donors in many of Kenya's hospital blood banks are either call responsive (CR) or walk-in (Wl) donors. These donors impact differently on the national blood transfusion services. Objective: ...

    • How important is the ‘quality’ of the cytotoxic T lymphocyte (CTL) response in protection against HIV infection? 

      Rowland-Jonesa, Sarah L.; Pinheiroa, Susana; Kaula, Rupert; Hansasutaa, Pokrath; Gillespiea, Geraldine; Donga, Tao; Plummerb, Francis A.; Bwayob, Job B.; Fidlerc, Sarah; Weberc, Jonathan; McMichaela, Andrew; Appaya, Victor (Department of Medical Microbiology, P.O. Box 19676, University of Nairobi, Nairobi, KenyaMRC Human Immunology Unit, Institute of Molecular Medicine, John Radcliffe Hospital, Headington, Oxford OX3 9DS, UKDepartment of Genito-Urinary Medicine, Imperial College School of Medicine at St. Mary's Hospital, Paddington, London, UK, 2001-11)
      Cytotoxic T lymphocyte (CTL) responses have been associated with protection from HIV-1 infection in people with a high degree of exposure to HIV and who show no serological evidence of HIV infection (HEPS, highly exposed ...

    • Neoplastic cells of Hodgkin's disease show differences in EBV expression between Kenya and Italy. 

      Tosi, P; Pileri, S; Poggi, S; Sabattini, E; De Vivo, A; De Luca, F; Disanto, A; Minacci, C; Abinya, O; Nyong'o, A; Spina, D; Leoncini, L (Department of Clinical Medicine and Therapeutics, 1996-03)
      The Epstein-Barr Virus (EBV) has been implicated in the pathogenesis of Hodgkin's disease (HD). However, the association of EBV with this disease varies greatly from series to series and from country to country. Epidemiological ...

    • “Once I begin to participate, people will run away from me”: Understanding stigma as a barrier to HIV vaccine research participation in Kenya 

      Nybladed, Laura; Singh, Sagri; Ashburn, Kim; Brady, Laura; Olenja, Joyce (Department of Community Health, University of NairobiResearch Triangle Institute InternationalInternational AIDS Vaccine InitiativeInternational Center for Research on Women, Washington, 2011-11)
      Purpose Participation of volunteers in clinical research is essential to the development of effective HIV prevention methods, including an HIV vaccine. This study expands current knowledge of stigma and discrimination ...

    • Treatment of Rhodesian sleeping sickness in Kenya. 

      Siongok, TA; Smith, DH; Mbwabi, D; Dola, S; Wanyama, L; Abinya, A; Reardon, MJ; Chumo, DA; Wellde, BT (Department of Clinical Medicine and Therapeutics, 1989-08)
      In a study of 269 sleeping sickness patients treated with Mel-B, 14 (5.2%) died during treatment. With total dosages of at least 30 ml (1.08 g), 1.4% relapsed and another 6.4% died, mostly of unknown causes, within three ...

    • Presenting features of Rhodosian sleeping sickness patients in the Lambwe Vallel in Kenya. 

      Smith, DH; Wanyama, L; Abinya, A; Mbwabi, D; Asenti, A; Mwangi, J; Reardon, MJ; Chumo, DA; Wellde, BT (Department of Clinical Medicine and Therapeutics, 1989-08)
      During a recent outbreak of Rhodesian sleeping sickness in the Lambwe Valley no asymptomatic Rhodesian sleeping sickness patients were found although 54% of the primary patients had mild symptoms and 9% were stuporous or ...

    • AIDS in Africa A Manual for Physicians, World Health Organization, Geneva (1992 

      Piot, Peter M.; Kapita, Bila; Ngugi, Elizabeth N; Mann, Jonathan M.; Colebunders, Robert; Wabitsch, Rudolph (Department of Medical Microbiology, University of Nairobi, Nairobi, Kenya, 1994)